1.0 2016-05-22 04:28:26 UTC 2026-08-22 02:01:40 UTC Mevastatin SmallMolecule Mevastatin is an organoheterocyclic compound with the formula $\text{C}_{23}\text{H}_{34}\text{O}_5$ and an average molecular weight of 390.52 g/mol. Mevastatin belongs to the delta valerolactones, a subclass of lactones within the organic compounds. In terms of biological activity, it is recorded as an inhibitor of the protein target 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR). The compound is found in or released from 37 recorded sources across multiple sectors. Within Electrical & Electronic Equipment, it is associated with cell phones, capacitors, wires and cables, batteries, printed circuit boards, and 10 additional sources. In Building & Construction, it is linked to ceilings, fencing, ladders, stairs and ramps, sunshades awnings or outside screens, and 2 others. Its presence is noted in Food, food processing & cookware, specifically regarding food packaging, food preservation, fermentation processes for beer, processing meats, and the preparation of wine or sparkling wine. Additional sources include healthcare, pharmaceuticals & veterinary products, such as medical devices and antibiotics; textiles, leather & furnishings, including carpets and rugs and synthetic textiles; and household cleaning & consumer products, such as soap detergents and perfumes within detergents and soaps, among 4 more sectors. Recorded routes of exposure for mevastatin include touch, oral, and inhalation. Mycotoxin PFAS C23H34O5 390.52 390.240624195 (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate mevastatin 73573-88-3 [H][C@]12[C@H](CCC=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1 AJLFOPYRIVGYMJ-INTXDZFKSA-N Organic compounds Organoheterocyclic compounds Lactones Delta valerolactones Delta valerolactones Carbonyl compounds Carboxylic acid esters Dicarboxylic acids and derivatives Fatty acid esters Hydrocarbon derivatives Organic oxides Oxacyclic compounds Oxanes Secondary alcohols Alcohol Aliphatic heteropolycyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Delta valerolactone Delta_valerolactone Dicarboxylic acid or derivatives Fatty acid ester Fatty acyl Hydrocarbon derivative Organic oxide Organic oxygen compound Organooxygen compound Oxacycle Oxane Secondary alcohol Aliphatic heteropolycyclic compounds carbobicyclic compound carboxylic ester delta-lactone statin (naturally occurring) Detected and Not Quantified logp 3.62 logp 4.13 ALOGPS logs -4.08 ALOGPS solubility 3.21e-02 g/l ALOGPS logp 3.62 ChemAxon pka_strongest_acidic 14.91 ChemAxon pka_strongest_basic -2.8 ChemAxon iupac (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate ChemAxon average_mass 390.52 ChemAxon mono_mass 390.240624195 ChemAxon smiles [H][C@]12[C@H](CCC=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC ChemAxon formula C23H34O5 ChemAxon inchi InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1 ChemAxon inchikey AJLFOPYRIVGYMJ-INTXDZFKSA-N ChemAxon polar_surface_area 72.83 ChemAxon refractivity 108.63 ChemAxon polarizability 43.57 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb3f36a60> DB06693 2854 2752 BE0000574