1.0 2016-05-22 04:28:32 UTC 2026-08-19 17:11:05 UTC Oxymetazoline SmallMolecule Oxymetazoline is an organic compound with the formula C16H24N2O and an average molecular weight of 260.37 g/mol. Oxymetazoline belongs to the xylenes, a subclass of benzene and substituted derivatives within the organic compounds. This compound is found in or released from 16 recorded sources. These include healthcare, pharmaceuticals, and veterinary products such as decongestants, antiallergics, nasal preparations, and dermatological preparations. It is also associated with household cleaning and consumer products, specifically perfumes within detergents and soaps, soap detergents, cigar cigarettes, other smoking requisites, and non electric simulated smoking devices. Additionally, it is linked to electrical and electronic equipment, including electrodes, power cables, hybrid capacitors, electric hearing aids, and electrically stimulated smoking devices. Other recorded sources include food preservation within food, food processing, and cookware, as well as stairs and ramps within building and construction. Recorded exposure routes for oxymetazoline include oral, nasal, topical, and ophthalmic pathways. At the molecular level, oxymetazoline interacts with 10 recorded protein targets. It acts as an agonist or partial agonist of the Alpha-1A adrenergic receptor (ADRA1A), as well as the Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C) adrenergic receptors, among six other proteins. C16H24N2O 260.3746 260.1888634 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol oxymetazoline 1491-59-4 CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) WYWIFABBXFUGLM-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Xylenes Xylenols Azacyclic compounds Carboxamidines Carboximidamides Hydrocarbon derivatives Imidazolines Imidolactams Organooxygen compounds Organopnictogen compounds Ortho cresols Para cresols Phenylpropanes Propargyl-type 1,3-dipolar organic compounds m-Xylenes 2-imidazoline Amidine Aromatic heteromonocyclic compound Azacycle Carboximidamide Carboxylic acid amidine Hydrocarbon derivative Imidolactam M-xylene O-cresol Organic 1,3-dipolar compound Organic nitrogen compound Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound P-cresol Phenol Phenylpropane Propargyl-type 1,3-dipolar organic compound Xylenol Aromatic heteromonocyclic compounds carboxamidine imidazolines phenols Detected and Not Quantified Oxymetazoline Drug Metabolism Action Pathway SMP0143367 logp 3.03 logp 3.70 ALOGPS logs -3.70 ALOGPS solubility 5.15e-02 g/l ALOGPS logp 3.03 ChemAxon pka_strongest_acidic 10.91 ChemAxon pka_strongest_basic 10.15 ChemAxon iupac 6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol ChemAxon average_mass 260.3746 ChemAxon mono_mass 260.1888634 ChemAxon smiles CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C ChemAxon formula C16H24N2O ChemAxon inchi InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) ChemAxon inchikey WYWIFABBXFUGLM-UHFFFAOYSA-N ChemAxon polar_surface_area 44.62 ChemAxon refractivity 79.8 ChemAxon polarizability 30.64 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72251f7e50> DB00935 4636 4475 BE0000501 BE0000289 BE0000342 BE0000572 BE0000575 BE0000715 BE0000291 BE0000797 BE0000659 BE0004882