1.0 2016-05-22 04:30:20 UTC 2026-08-19 06:02:54 UTC Imiquimod SmallMolecule Imiquimod is an organic compound with the formula C14H16N4 and an average molecular weight of 240.30 g/mol. Imiquimod belongs to the imidazoquinolines, a subclass of quinolines and derivatives within the organic compounds. Biologically, it functions as an agonist (PMC6331894, PMC8197201). It acts as an agonist of two recorded protein targets: Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). In medical applications, imiquimod is used as a treatment for basal cell carcinoma (PMC9266369) and skin cancer (PMC8197201). Additionally, it is associated with psoriasis (PMC12028938). Within the category of healthcare, pharmaceuticals, and veterinary products, it is classified as a chemotherapeutic. The compound is found in or released from ten recorded sources. These include household cleaning and consumer products such as non-electric simulated smoking devices, cigar cigarettes, and other smoking requisites. It is also found in electrical and electronic equipment, including television systems, video games, antennas, line transmission systems, and electrically stimulated smoking devices. Further sources include indoor air, dust, and atmospheric transport. Recorded exposure routes for the compound include topical application and inhalation. Human Neurotoxin C14H16N4 240.3036 240.137496532 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine imiquimod 99011-02-6 CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17) DOUYETYNHWVLEO-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Quinolines and derivatives Imidazoquinolines Imidazoquinolines Aminopyridines and derivatives Aminoquinolines and derivatives Azacyclic compounds Benzenoids Heteroaromatic compounds Hydrocarbon derivatives Imidazo-[4,5-c]pyridines Imidolactams N-substituted imidazoles Organopnictogen compounds Primary amines Amine Aminopyridine Aminoquinoline Aromatic heteropolycyclic compound Azacycle Azole Benzenoid Heteroaromatic compound Hydrocarbon derivative Imidazo-[4,5-c]pyridine Imidazole Imidazopyridine Imidazoquinoline Imidolactam N-substituted imidazole Organic nitrogen compound Organonitrogen compound Organopnictogen compound Primary amine Pyridine Aromatic heteropolycyclic compounds imidazoquinoline Detected and Not Quantified Toll-Like Receptor Pathway 2 SMP0069593 Imiquimod Drug Metabolism Action Pathway SMP0143168 logp 2.65 logp 2.83 ALOGPS logs -2.99 ALOGPS solubility 2.47e-01 g/l ALOGPS logp 2.65 ChemAxon pka_strongest_basic 5.4 ChemAxon iupac 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine ChemAxon average_mass 240.3036 ChemAxon mono_mass 240.137496532 ChemAxon smiles CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N ChemAxon formula C14H16N4 ChemAxon inchi InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17) ChemAxon inchikey DOUYETYNHWVLEO-UHFFFAOYSA-N ChemAxon polar_surface_area 56.73 ChemAxon refractivity 72.54 ChemAxon polarizability 26.67 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baeca5e68> DB00724 57469 51809 BE0000155 BE0003518