1.0 2016-05-22 04:41:09 UTC 2026-08-19 21:55:49 UTC Amisulpride SmallMolecule Amisulpride is an organic compound with the formula C17H27N3O4S and an average molecular weight of 369.48 g/mol. Amisulpride belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. The substance is identified as being found in or released from five recorded sources. These include healthcare, pharmaceuticals, and veterinary products where it is used as an antipsychotic, as well as electrical and electronic equipment, specifically radio transmission systems and electrically stimulated smoking devices. Additionally, it is found in household cleaning and consumer products, including tobacco smoke filters and non-electric simulated smoking devices. The recorded route of exposure for this compound is intravenous. In terms of its biological activity, amisulpride interacts with seven recorded protein targets. It acts as an agonist or antagonist of the D(2) dopamine receptor (DRD2), the D(3) dopamine receptor (DRD3), 5-hydroxytryptamine receptor 7 (HTR7), and 5-hydroxytryptamine receptor 2A (HTR2A), in addition to three other proteins. Human Neurotoxin C17H27N3O4S 369.479 369.172227057 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide amisulpride 71675-85-9 CCN1CCCC1CNC(=O)C1=CC(=C(N)C=C1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Aminobenzamides Alkyl aryl ethers Amino acids and derivatives Aminophenyl ethers Anisoles Azacyclic compounds Benzamides Benzenesulfonyl compounds Benzoyl derivatives Hydrocarbon derivatives Methoxyanilines Methoxybenzenes N-alkylpyrrolidines Organic oxides Organopnictogen compounds Phenoxy compounds Primary amines Secondary carboxylic acid amides Sulfones Trialkylamines Alkyl aryl ether Amine Amino acid or derivatives Aminobenzamide Aminophenyl ether Aniline or substituted anilines Anisole Aromatic heteromonocyclic compound Azacycle Benzamide Benzenesulfonyl group Benzoyl Carboxamide group Carboxylic acid derivative Ether Hydrocarbon derivative Methoxyaniline Methoxybenzene N-alkylpyrrolidine Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Phenol ether Phenoxy compound Primary amine Pyrrolidine Secondary carboxylic acid amide Sulfone Sulfonyl Tertiary aliphatic amine Tertiary amine Aromatic heteromonocyclic compounds aromatic amide aromatic amine benzamides pyrrolidines sulfone Detected and Not Quantified Amisulpride Serotonin Antagonist Action Pathway SMP0126531 Amisulpride Drug Metabolism Action Pathway SMP0144034 Amisulpride Predicted Metabolism Pathway SMP0174696 logp 0.25 logp 1.50 ALOGPS logs -3.10 ALOGPS solubility 2.93e-01 g/l ALOGPS logp 0.25 ChemAxon pka_strongest_acidic 14.03 ChemAxon pka_strongest_basic 7.05 ChemAxon iupac 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide ChemAxon average_mass 369.479 ChemAxon mono_mass 369.172227057 ChemAxon smiles CCN1CCCC1CNC(=O)C1=CC(=C(N)C=C1OC)S(=O)(=O)CC ChemAxon formula C17H27N3O4S ChemAxon inchi InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) ChemAxon inchikey NTJOBXMMWNYJFB-UHFFFAOYSA-N ChemAxon polar_surface_area 101.73 ChemAxon refractivity 99.84 ChemAxon polarizability 39.82 ChemAxon rotatable_bond_count 7 ChemAxon acceptor_count 6 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72704acee8> DB06288 2159 2074 BE0000756 BE0000581 BE0000650 BE0000451 BE0000770 BE0000420 BE0000632