1.0 2016-05-22 04:41:25 UTC 2026-08-24 15:07:10 UTC Cidofovir SmallMolecule Cidofovir is an organic compound with the formula C8H14N3O6P and an average molecular weight of 279.19 g/mol. Cidofovir belongs to the pyrimidines and pyrimidine derivatives, a subclass of diazines within the organic compounds. It is classified as an organoheterocyclic compound. The substance is found in or released from healthcare, pharmaceuticals, and veterinary products as an antiviral. The recorded exposure route for this compound is intravenous. Regarding its biological activity, Cidofovir has two recorded protein targets: the DNA polymerase catalytic subunit and the DNA polymerase catalytic subunit (UL54), for which it acts as an inhibitor or modulator. C8H14N3O6P 279.187 279.062021707 ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid cidofovir 113852-37-2 NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1 InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1 VWFCHDSQECPREK-LURJTMIESA-N Organic compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Pyrimidones Aminopyrimidines and derivatives Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Imidolactams Organic oxides Organic phosphonic acids Organophosphorus compounds Organopnictogen compounds Primary alcohols Primary amines Alcohol Amine Aminopyrimidine Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Imidolactam Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organophosphonic acid Organophosphonic acid derivative Organophosphorus compound Organopnictogen compound Primary alcohol Primary amine Pyrimidone Aromatic heteromonocyclic compounds phosphonic acids pyrimidone Detected and Not Quantified Cidofovir Action Pathway SMP0125884 Brincidofovir Action Pathway SMP0125890 Cidofovir Drug Metabolism Action Pathway SMP0142827 logp -2.4 logp -2.12 ALOGPS logs -1.38 ALOGPS solubility 1.15e+01 g/l ALOGPS logp -3.4 ChemAxon pka_strongest_acidic 1.19 ChemAxon pka_strongest_basic 2.15 ChemAxon iupac ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid ChemAxon average_mass 279.187 ChemAxon mono_mass 279.062021707 ChemAxon smiles NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1 ChemAxon formula C8H14N3O6P ChemAxon inchi InChI=1S/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/m0/s1 ChemAxon inchikey VWFCHDSQECPREK-LURJTMIESA-N ChemAxon polar_surface_area 145.68 ChemAxon refractivity 60.43 ChemAxon polarizability 24.44 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 8 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f722411baf0> DB00369 466146 409759 BE0000343 BE0000308