1.0 2016-05-22 04:42:28 UTC 2026-08-19 08:30:43 UTC Triclabendazole SmallMolecule Triclabendazole is an organic compound with the chemical formula $\text{C}_{14}\text{H}_9\text{Cl}_3\text{N}_2\text{OS}$ and an average molecular weight of 359.65 g/mol. Triclabendazole belongs to the ethers, a subclass of organooxygen compounds within the organic compounds. This compound is associated with one recorded source: healthcare, pharmaceuticals & veterinary products, where it is utilized as an anthelmintic. The recorded route of exposure for this substance is oral. In terms of biological activity, there are five recorded protein targets for triclabendazole. It acts as an inhibitor of the Glutathione S-transferase omega class, and its targets include the Glutathione S-transferase omega class (Cat-1), the Glutathione S-transferase omega class (ENO), the Glutathione S-transferase omega class (ND3), and one other protein. C14H9Cl3N2OS 359.65 357.9501172 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole triclabendazole 68786-66-3 CSC1=NC2=C(N1)C=C(Cl)C(OC1=CC=CC(Cl)=C1Cl)=C2 InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19) NQPDXQQQCQDHHW-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Ethers Diarylethers Alkylarylthioethers Aryl chlorides Azacyclic compounds Benzimidazoles Dichlorobenzenes Heteroaromatic compounds Hydrocarbon derivatives Imidazoles Organochlorides Organonitrogen compounds Organopnictogen compounds Phenol ethers Phenoxy compounds Sulfenyl compounds 1,2-dichlorobenzene Alkylarylthioether Aromatic heteropolycyclic compound Aryl chloride Aryl halide Aryl thioether Azacycle Azole Benzenoid Benzimidazole Chlorobenzene Diaryl ether Halobenzene Heteroaromatic compound Hydrocarbon derivative Imidazole Monocyclic benzene moiety Organic nitrogen compound Organochloride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Organosulfur compound Phenol ether Phenoxy compound Sulfenyl compound Thioether Aromatic heteropolycyclic compounds Detected and Not Quantified Triclabendazole Drug Metabolism Action Pathway SMP0144838 logp 5.88 logp 5.50 ALOGPS logs -5.85 ALOGPS solubility 5.08e-04 g/l ALOGPS logp 5.88 ChemAxon pka_strongest_acidic 10.46 ChemAxon pka_strongest_basic 4.54 ChemAxon iupac 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylsulfanyl)-1H-1,3-benzodiazole ChemAxon average_mass 359.65 ChemAxon mono_mass 357.9501172 ChemAxon smiles CSC1=NC2=C(N1)C=C(Cl)C(OC1=CC=CC(Cl)=C1Cl)=C2 ChemAxon formula C14H9Cl3N2OS ChemAxon inchi InChI=1S/C14H9Cl3N2OS/c1-21-14-18-9-5-8(16)12(6-10(9)19-14)20-11-4-2-3-7(15)13(11)17/h2-6H,1H3,(H,18,19) ChemAxon inchikey NQPDXQQQCQDHHW-UHFFFAOYSA-N ChemAxon polar_surface_area 37.91 ChemAxon refractivity 87.86 ChemAxon polarizability 34.02 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721b72b688> DB12245 50248 45565 BE0009630 BE0001292