1.0 2016-05-22 05:02:03 UTC 2026-08-18 00:06:31 UTC 1-(3-Chlorophenyl)piperazine SmallMolecule 1-(3-Chlorophenyl)piperazine is an organic compound with the formula C10H13ClN2 and an average molecular weight of 196.68 g/mol. 1-(3-Chlorophenyl)piperazine belongs to the piperazines, a subclass of diazinanes within the organic compounds. This substance is identified as an organoheterocyclic compound. The compound has been found in or released from 23 recorded sources. These include aquatic systems and sediments such as seawater, freshwater, surface water, and groundwater, as well as drinking water and water supply sources including tap water, bottled water, desalinated water, and drinking water. It is also present in wastewater, sanitation, and biosolids, specifically in industrial wastewater, mine wastewater, wastewater treatment effluent, and unspecified wastewater. Other recorded sources involve appliances, HVAC, and refrigerants such as water heaters and water coolers, as well as marine, shipping, and aquaculture sources including bilge water and ballast water. Additionally, it is associated with electrical and electronic equipment, specifically electrodes and conductors or conductive bodies characterized by the conductive materials, among four other sectors. Exposure to the compound can occur through touch, oral, and inhalation routes. Biologically, 1-(3-Chlorophenyl)piperazine interacts with seven recorded protein targets. It acts as an agonist/antagonist of 5-hydroxytryptamine receptor 2C (HTR2C), 5-hydroxytryptamine receptor 1E (HTR1E), 5-hydroxytryptamine receptor 7 (HTR7), and 5-hydroxytryptamine receptor 6 (HTR6), in addition to three other proteins. Human Neurotoxin PMT C10H13ClN2 196.677 196.076726133 1-(3-chlorophenyl)piperazine m-chlorophenylpiperazine 6640-24-0 ClC1=CC(=CC=C1)N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 VHFVKMTVMIZMIK-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Diazinanes Piperazines Phenylpiperazines Aniline and substituted anilines Aryl chlorides Azacyclic compounds Chlorobenzenes Dialkylamines Dialkylarylamines Hydrocarbon derivatives N-arylpiperazines Organochlorides Organopnictogen compounds Amine Aniline or substituted anilines Aromatic heteromonocyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Chlorobenzene Dialkylarylamine Halobenzene Hydrocarbon derivative Monocyclic benzene moiety N-arylpiperazine Organic nitrogen compound Organochloride Organohalogen compound Organonitrogen compound Organopnictogen compound Phenylpiperazine Secondary aliphatic amine Secondary amine Tertiary aliphatic/aromatic amine Tertiary amine Aromatic heteromonocyclic compounds N-arylpiperazine monochlorobenzenes Detected and Not Quantified logp 2.15 logp 2.07 ALOGPS logs -1.80 ALOGPS solubility 3.12e+00 g/l ALOGPS logp 2.15 ChemAxon pka_strongest_basic 8.87 ChemAxon iupac 1-(3-chlorophenyl)piperazine ChemAxon average_mass 196.677 ChemAxon mono_mass 196.076726133 ChemAxon smiles ClC1=CC(=CC=C1)N1CCNCC1 ChemAxon formula C10H13ClN2 ChemAxon inchi InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 ChemAxon inchikey VHFVKMTVMIZMIK-UHFFFAOYSA-N ChemAxon polar_surface_area 15.27 ChemAxon refractivity 56.05 ChemAxon polarizability 20.87 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7267c9ff00> DB12110 1355 1314 BE0000533 BE0000476 BE0000650 BE0000945 BE0000451 BE0000393 BE0000659