1.0 2016-05-22 05:11:54 UTC 2026-08-21 19:49:26 UTC Disopyramide SmallMolecule Disopyramide is an organic compound with the chemical formula C21H29N3O and an average molecular weight of 339.47 g/mol. Disopyramide belongs to the pheniramines, a subclass of pyridines and derivatives within the organic compounds. This compound is recorded as being found in or released from seven different sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is utilized as a class I and III antiarrhythmic. Other recorded sources include household cleaning and consumer products, specifically tobacco smoke filters, cigar cigarettes, non-electric simulated smoking devices, and other smoking requisites. It is also associated with electrical and electronic equipment, including electrically stimulated smoking devices and conductive bodies characterized by their conductive materials. The recorded route of exposure for this substance is oral. At the molecular level, disopyramide interacts with eight recorded protein targets. It functions as an antagonist, binder, or inhibitor of the sodium channel protein type 5 subunit alpha (SCN5A), as well as the muscarinic acetylcholine receptors M1 (CHRM1), M2 (CHRM2), and M3 (CHRM3). Additionally, it targets four other proteins. Human Neurotoxin C21H29N3O 339.4745 339.231062565 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide disopyramide 3737-09-5 CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C1=NC=CC=C1)C(C)C InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25) UVTNFZQICZKOEM-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Pyridines and derivatives Pheniramines Pheniramines Aralkylamines Azacyclic compounds Benzene and substituted derivatives Carboximidic acids Heteroaromatic compounds Hydrocarbon derivatives Organooxygen compounds Organopnictogen compounds Trialkylamines Amine Aralkylamine Aromatic heteromonocyclic compound Azacycle Benzenoid Carboximidic acid Carboximidic acid derivative Heteroaromatic compound Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Pheniramine Tertiary aliphatic amine Tertiary amine Aromatic heteromonocyclic compounds monocarboxylic acid amide pyridines tertiary amino compound Detected and Not Quantified Disopyramide Action Pathway SMP0000325 Disopyramide Cardiac Action Pathway SMP0126247 Disopyramide Drug Metabolism Action Pathway SMP0142740 logp 3.47 logp 3.21 ALOGPS logs -3.84 ALOGPS solubility 4.93e-02 g/l ALOGPS logp 3.47 ChemAxon pka_strongest_acidic 16.19 ChemAxon pka_strongest_basic 10.42 ChemAxon iupac 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide ChemAxon average_mass 339.4745 ChemAxon mono_mass 339.231062565 ChemAxon smiles CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C1=NC=CC=C1)C(C)C ChemAxon formula C21H29N3O ChemAxon inchi InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25) ChemAxon inchikey UVTNFZQICZKOEM-UHFFFAOYSA-N ChemAxon polar_surface_area 59.22 ChemAxon refractivity 102.3 ChemAxon polarizability 38.82 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb3b550b8> DB00280 3114 3002 BE0000197 BE0000092 BE0000560 BE0000045 BE0003603 BE0003604 BE0000090 BE0003663