1.0 2016-05-22 05:24:14 UTC 2026-05-14 19:33:15 UTC Edoxudine SmallMolecule Edoxudine is an organic compound with the chemical formula C11H16N2O5 and an average molecular weight of 256.26 g/mol. Edoxudine belongs to the pyrimidine 2'-deoxyribonucleosides, a subclass of pyrimidine nucleosides within the organic compounds. This compound is associated with four recorded sources, including healthcare, pharmaceuticals and veterinary products where it is used as a chemotherapeutic agent. It is also found in television systems and video games categorized under electrical and electronic equipment, as well as non-electric simulated smoking devices categorized under household cleaning and consumer products. The recorded route of exposure for this substance is topical. In terms of biological activity, edoxudine interacts with two recorded protein targets, acting as an inhibitor of DNA polymerase (DNApol) and thymidine kinase, cytosolic (TK1). C11H16N2O5 256.258 256.105921623 5-ethyl-4-hydroxy-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one β-5-ethyl-2'-deoxyuridine 15176-29-1 [H][C@]1(O)C[C@@]([H])(O[C@]1([H])CO)N1C=C(CC)C(O)=NC1=O InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1 XACKNLSZYYIACO-DJLDLDEBSA-N Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleosides Pyrimidine 2'-deoxyribonucleosides Pyrimidine 2'-deoxyribonucleosides Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Primary alcohols Pyrimidones Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides Alcohol Aromatic heteromonocyclic compound Azacycle Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Primary alcohol Pyrimidine Pyrimidine 2'-deoxyribonucleoside Pyrimidone Secondary alcohol Tetrahydrofuran Urea Vinylogous amide Aromatic heteromonocyclic compounds Detected and Not Quantified Edoxudine Action Pathway SMP0125881 Edoxudine Drug Metabolism SMP0130750 Edoxudine Drug Metabolism Action Pathway SMP0144984 logp -0.67 logp -1.40 ALOGPS logs -1.38 ALOGPS solubility 1.06e+01 g/l ALOGPS logp -0.31 ChemAxon pka_strongest_acidic 7.56 ChemAxon pka_strongest_basic -3 ChemAxon iupac 5-ethyl-4-hydroxy-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one ChemAxon average_mass 256.258 ChemAxon mono_mass 256.105921623 ChemAxon smiles [H][C@]1(O)C[C@@]([H])(O[C@]1([H])CO)N1C=C(CC)C(O)=NC1=O ChemAxon formula C11H16N2O5 ChemAxon inchi InChI=1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1 ChemAxon inchikey XACKNLSZYYIACO-DJLDLDEBSA-N ChemAxon polar_surface_area 102.59 ChemAxon refractivity 60.33 ChemAxon polarizability 24.74 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 6 ChemAxon donor_count 3 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72a02bf3d0> DB13421 66377 59752 BE0009350 BE0001260