1.0 2016-05-22 05:44:30 UTC 2026-05-14 19:28:54 UTC Biapenem SmallMolecule Biapenem is an organic compound with the chemical formula C15H18N4O4S and an average molecular weight of 350.39 g/mol. Biapenem belongs to the beta lactams, a subclass of lactams within the organic compounds. It is further classified within the superclass of organoheterocyclic compounds. The compound is identified in five recorded sources, which include antibiotics within healthcare, pharmaceuticals, and veterinary products, as well as electrical and electronic equipment such as communication cables or conductors, radio transmission systems, line transmission systems, and antennas. Recorded routes of exposure for this substance include oral and inhalation. In terms of biological activity, biapenem interacts with seven recorded protein targets. It acts as an inhibitor of penicillin-binding protein 1A (mrcA), penicillin-binding protein 1B (mrcB), D-alanyl-D-alanine carboxypeptidase DacC (dacC), and peptidoglycan D,D-transpeptidase MrdA (mrdA), in addition to three other proteins. C15H18N4O4S 350.39 350.10487625 6-{[(4R,5S,6S)-2-carboxylato-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]sulfanyl}-5H,6H,7H-4λ⁵-pyrazolo[1,2-a][1,2,4]triazol-4-ylium biapenem 120410-24-4 [H][C@](C)(O)[C@@]1([H])C(=O)N2C(C([O-])=O)=C(SC3CN4C=NC=[N+]4C3)[C@]([H])(C)[C@]12[H] InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1 MRMBZHPJVKCOMA-YJFSRANCSA-N Organic compounds Organoheterocyclic compounds Lactams Beta lactams Thienamycins Alpha amino acids and derivatives Azacyclic compounds Azepines Azetidines Carbonyl compounds Carboxylic acid salts Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organic salts Organic zwitterions Organonitrogen compounds Organopnictogen compounds Pyrroline carboxylic acids Secondary alcohols Sulfenyl compounds Tertiary carboxylic acid amides Thioenol ethers Triazoles Vinylogous thioesters 1,2,4-triazole Alcohol Alpha-amino acid or derivatives Aromatic heteropolycyclic compound Azacycle Azepine Azetidine Azole Carbonyl group Carboxamide group Carboxylic acid Carboxylic acid derivative Carboxylic acid salt Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organic salt Organic zwitterion Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Pyrroline Pyrroline carboxylic acid Pyrroline carboxylic acid or derivatives Secondary alcohol Sulfenyl compound Tertiary carboxylic acid amide Thienamycin Thioenolether Vinylogous thioester Aromatic heteropolycyclic compounds carbapenems organic sulfide pyrazolotriazole Detected and Not Quantified logp -6.1 logp -1.97 ALOGPS logs -2.17 ALOGPS solubility 2.75e+00 g/l ALOGPS logp -6.1 ChemAxon pka_strongest_acidic 3.51 ChemAxon pka_strongest_basic -1.6 ChemAxon iupac 6-{[(4R,5S,6S)-2-carboxylato-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-en-3-yl]sulfanyl}-5H,6H,7H-4λ⁵-pyrazolo[1,2-a][1,2,4]triazol-4-ylium ChemAxon average_mass 350.39 ChemAxon mono_mass 350.10487625 ChemAxon smiles [H][C@](C)(O)[C@@]1([H])C(=O)N2C(C([O-])=O)=C(SC3CN4C=NC=[N+]4C3)[C@]([H])(C)[C@]12[H] ChemAxon formula C15H18N4O4S ChemAxon inchi InChI=1S/C15H18N4O4S/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)24-9-3-17-5-16-6-18(17)4-9/h5-11,20H,3-4H2,1-2H3/t7-,8-,10-,11-/m1/s1 ChemAxon inchikey MRMBZHPJVKCOMA-YJFSRANCSA-N ChemAxon polar_surface_area 102.37 ChemAxon refractivity 120.82 ChemAxon polarizability 35.06 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7222d4a508> DB13028 71339 64442 BE0000588 BE0000488 BE0003685 BE0003579 BE0002393 BE0002063 BE0000744