1.0 2016-05-22 05:45:10 UTC 2026-08-21 21:37:35 UTC Rimonabant SmallMolecule Rimonabant is an organic compound with the chemical formula C22H21Cl3N4O and an average molecular weight of 463.79 g/mol. Rimonabant belongs to the pyrazoles, a subclass of azoles within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds. The compound acts as an antagonist for two recorded protein targets: G-protein coupled receptor 55 (GPR55) and Cannabinoid receptor 1 (CNR1). Rimonabant has been identified in four recorded sources, including healthcare, pharmaceuticals, and veterinary products, specifically as antiobesity preparations excluding diet products. Additionally, it is found in household cleaning and consumer products, such as tobacco product cases, other smoking requisites, and non electric simulated smoking devices. The recorded route of exposure for this compound is oral. C22H21Cl3N4O 463.787 462.078094435 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide rimonabant 168273-06-1 CC1=C(N(N=C1C(=O)NN1CCCCC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(Cl)C=C1 InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) JZCPYUJPEARBJL-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Azoles Pyrazoles Phenylpyrazoles Aryl chlorides Azacyclic compounds Dichlorobenzenes Heteroaromatic compounds Hydrazones Hydrocarbon derivatives Organochlorides Organooxygen compounds Organopnictogen compounds Piperidines 1,3-dichlorobenzene Aromatic heteromonocyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Chlorobenzene Halobenzene Heteroaromatic compound Hydrazone Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenylpyrazole Piperidine Aromatic heteromonocyclic compounds pyrazoles ring assembly Detected and Not Quantified Rimonabant Drug Metabolism SMP0130781 Rimonabant Drug Metabolism Action Pathway SMP0143999 logp 5.91 logp 5.47 ALOGPS logs -5.36 ALOGPS solubility 2.00e-03 g/l ALOGPS logp 5.91 ChemAxon pka_strongest_acidic 12.42 ChemAxon pka_strongest_basic 1.68 ChemAxon iupac 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide ChemAxon average_mass 463.787 ChemAxon mono_mass 462.078094435 ChemAxon smiles CC1=C(N(N=C1C(=O)NN1CCCCC1)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(Cl)C=C1 ChemAxon formula C22H21Cl3N4O ChemAxon inchi InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) ChemAxon inchikey JZCPYUJPEARBJL-UHFFFAOYSA-N ChemAxon polar_surface_area 50.16 ChemAxon refractivity 122.83 ChemAxon polarizability 47.96 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7223448a30> DB06155 104850 94641 BE0000061 BE0005802