1.0 2016-05-22 05:45:33 UTC 2026-05-14 17:00:04 UTC Drospirenone SmallMolecule Drospirenone is an organic compound with the chemical formula C24H30O3 and an average molecular weight of 366.49 g/mol. Drospirenone belongs to the steroid lactones, a subclass of steroids and steroid derivatives within the organic compounds. This substance is categorized under the superclass of lipids and lipid-like molecules. The compound is found in or released from five recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically progestogens and estrogens in combination and hormonal contraceptives for systemic use. It is also associated with indoor air in the category of air, dust, and atmospheric transport, as well as antennas within electrical and electronic equipment. Additionally, it is found in non-electric simulated smoking devices among household cleaning and consumer products. Recorded routes of exposure include oral and inhalation. Drospirenone interacts with four recorded protein targets. It functions as an agonist, antagonist, or binder of the progesterone receptor (PGR), the mineralocorticoid receptor (NR3C2), the androgen receptor (AR), and the glucocorticoid receptor (NR3C1). C24H30O3 366.4932 366.219494826 (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0²,⁴.0⁵,¹⁰.0¹⁴,¹⁹.0¹⁶,¹⁸]nonadecane-15,2'-oxolan]-5-ene-5',7-dione yasmin 67392-87-4 [H][C@@]12C[C@]1([H])[C@@]1([H])[C@]3([H])[C@]4([H])C[C@]4([H])[C@@]4(CCC(=O)O4)[C@@]3(C)CC[C@]1([H])[C@@]1(C)CCC(=O)C=C21 InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1 METQSPRSQINEEU-HXCATZOESA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Steroid lactones Spironolactones and derivatives Carboxylic acid esters Cyclohexenones Gamma butyrolactones Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Oxacyclic compounds Tetrahydrofurans Aliphatic heteropolycyclic compound Carbonyl group Carboxylic acid derivative Carboxylic acid ester Cyclic ketone Cyclohexenone Gamma butyrolactone Hydrocarbon derivative Ketone Lactone Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Spironolactone Tetrahydrofuran Aliphatic heteropolycyclic compounds 3-oxo Delta(4)-steroid 3-oxo steroid steroid lactone Detected and Not Quantified Drospirenone Action Pathway SMP0126538 Drospirenone Drug Metabolism Action Pathway SMP0143742 logp 3.37 logp 2.36 ALOGPS logs -5.21 ALOGPS solubility 2.25e-03 g/l ALOGPS logp 3.37 ChemAxon pka_strongest_basic -5 ChemAxon iupac (1R,2R,4R,10R,11S,14S,15S,16S,18S,19S)-10,14-dimethylspiro[hexacyclo[9.8.0.0²,⁴.0⁵,¹⁰.0¹⁴,¹⁹.0¹⁶,¹⁸]nonadecane-15,2'-oxolan]-5-ene-5',7-dione ChemAxon average_mass 366.4932 ChemAxon mono_mass 366.219494826 ChemAxon smiles [H][C@@]12C[C@]1([H])[C@@]1([H])[C@]3([H])[C@]4([H])C[C@]4([H])[C@@]4(CCC(=O)O4)[C@@]3(C)CC[C@]1([H])[C@@]1(C)CCC(=O)C=C21 ChemAxon formula C24H30O3 ChemAxon inchi InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1 ChemAxon inchikey METQSPRSQINEEU-HXCATZOESA-N ChemAxon polar_surface_area 43.37 ChemAxon refractivity 101.68 ChemAxon polarizability 41.81 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f722398c280> DB01395 68873 62105 BE0000557 BE0000668 BE0000132 BE0000794