1.0 2016-05-22 05:52:07 UTC 2026-08-22 10:59:33 UTC Ciclesonide SmallMolecule Ciclesonide belongs to the pregnane steroids, a subclass of steroids and steroid derivatives within the organic compounds. With an average molecular weight of 540.70 g/mol, Ciclesonide is a heavy molecule. Its chemical formula is C32H44O7. This compound is found in or released from four recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is used in nasal preparations and drugs for obstructive airway diseases. Additionally, it is associated with household cleaning and consumer products, specifically pipe accessories and other smoking requisites. Recorded exposure routes for the substance include respiratory and nasal administration. In terms of biological activity, Ciclesonide interacts with two recorded protein targets. It acts as an agonist or binder of the glucocorticoid receptor (NR3C1) and also interacts with corticosteroid-binding globulin (SERPINA6). C32H44O7 540.697 540.308703757 2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosa-14,17-dien-8-yl]-2-oxoethyl 2-methylpropanoate ciclesonide 141845-82-1 [H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(O[C@@H](O2)C1CCCCC1)C(=O)COC(=O)C(C)C InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1 LUKZNWIVRBCLON-GXOBDPJESA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Pregnane steroids Gluco/mineralocorticoids, progestogins and derivatives 1,3-dioxolanes 11-beta-hydroxysteroids 20-oxosteroids 3-oxo delta-1,4-steroids Acetals Alpha-acyloxy ketones Carboxylic acid esters Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Oxacyclic compounds Secondary alcohols 11-beta-hydroxysteroid 11-hydroxysteroid 20-oxosteroid 3-oxo-delta-1,4-steroid 3-oxosteroid Acetal Alcohol Aliphatic heteropolycyclic compound Alpha-acyloxy ketone Carbonyl group Carboxylic acid derivative Carboxylic acid ester Cyclic alcohol Cyclic ketone Delta-1,4-steroid Hydrocarbon derivative Hydroxysteroid Ketone Meta-dioxolane Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Oxosteroid Progestogin-skeleton Secondary alcohol Aliphatic heteropolycyclic compounds Detected and Not Quantified Ciclesonide Action Pathway SMP0126184 Ciclesonide Drug Metabolism Action Pathway SMP0143751 logp 5.32 logp 4.08 ALOGPS logs -5.54 ALOGPS solubility 1.57e-03 g/l ALOGPS logp 5.32 ChemAxon pka_strongest_acidic 14.78 ChemAxon pka_strongest_basic -2.9 ChemAxon iupac 2-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-6-cyclohexyl-11-hydroxy-9,13-dimethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0²,⁹.0⁴,⁸.0¹³,¹⁸]icosa-14,17-dien-8-yl]-2-oxoethyl 2-methylpropanoate ChemAxon average_mass 540.697 ChemAxon mono_mass 540.308703757 ChemAxon smiles [H][C@@]12C[C@@]3([H])[C@]4([H])CCC5=CC(=O)C=C[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(O[C@@H](O2)C1CCCCC1)C(=O)COC(=O)C(C)C ChemAxon formula C32H44O7 ChemAxon inchi InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1 ChemAxon inchikey LUKZNWIVRBCLON-GXOBDPJESA-N ChemAxon polar_surface_area 99.13 ChemAxon refractivity 146.28 ChemAxon polarizability 60.18 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 6 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727ae11e20> DB01410 6918155 5293368 BE0000794 BE0000209