1.0 2016-05-22 05:53:07 UTC 2026-08-21 18:38:08 UTC Tazarotene SmallMolecule Tazarotene is an organic compound with the formula C21H21NO2S and an average molecular weight of 351.46 g/mol. Tazarotene belongs to the retinoids, a subclass of prenol lipids within the organic compounds. In industrial applications, it serves as a softener and conditioner. Within the healthcare and pharmaceutical sectors, it is utilized as an antipsoriatic. The compound is found in or released from 19 recorded sources. These include electrical and electronic equipment, such as electrodes, hybrid capacitors, antennas, conductors or conductive bodies characterised by the conductive materials, and electrically stimulated smoking devices. In the category of household cleaning and consumer products, it is associated with soap detergents, perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is found in building and construction materials, specifically floors, stairs and ramps, as well as in food processing and cookware related to food preservation and the preparation of vinegar. Recorded exposure routes for the compound include oral, topical, and cutaneous paths. Tazarotene acts on four recorded protein targets, functioning as an agonist of Retinoic acid receptor alpha (RARA), Retinoic acid receptor beta (RARB), Retinoic acid receptor gamma (RARG), and Retinoic acid receptor RXR-beta (RXRB). C21H21NO2S 351.462 351.129299611 ethyl 6-[2-(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]pyridine-3-carboxylate tazarotene 118292-40-3 CCOC(=O)C1=CN=C(C=C1)C#CC1=CC2=C(SCCC2(C)C)C=C1 InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3 OGQICQVSFDPSEI-UHFFFAOYSA-N Organic compounds Lipids and lipid-like molecules Prenol lipids Retinoids Retinoids 1-benzothiopyrans Alkylarylthioethers Azacyclic compounds Benzenoids Carboxylic acid esters Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Pyridinecarboxylic acids Thiochromanes Thiopyrans 1-benzothiopyran Alkylarylthioether Aromatic heteropolycyclic compound Aryl thioether Azacycle Benzenoid Benzothiopyran Carboxylic acid derivative Carboxylic acid ester Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Tazarotene Thiochromane Thioether Thiopyran Aromatic heteropolycyclic compounds acetylenic compound ethyl ester pyridines retinoid thiochromane Detected and Not Quantified Tazarotene Drug Metabolism Action Pathway SMP0143238 logp 5.22 logp 5.15 ALOGPS logs -5.67 ALOGPS solubility 7.50e-04 g/l ALOGPS logp 5.22 ChemAxon pka_strongest_basic 1.23 ChemAxon iupac ethyl 6-[2-(4,4-dimethyl-3,4-dihydro-2H-1-benzothiopyran-6-yl)ethynyl]pyridine-3-carboxylate ChemAxon average_mass 351.462 ChemAxon mono_mass 351.129299611 ChemAxon smiles CCOC(=O)C1=CN=C(C=C1)C#CC1=CC2=C(SCCC2(C)C)C=C1 ChemAxon formula C21H21NO2S ChemAxon inchi InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3 ChemAxon inchikey OGQICQVSFDPSEI-UHFFFAOYSA-N ChemAxon polar_surface_area 39.19 ChemAxon refractivity 97.88 ChemAxon polarizability 40.31 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72730bf148> DB00799 5381 5188 BE0000663 BE0000078 BE0000144 BE0000206