1.0 2016-05-22 05:53:37 UTC 2026-08-19 15:07:45 UTC Pazufloxacin SmallMolecule Pazufloxacin is an organic compound with the formula C16H15FN2O4 and an average molecular weight of 318.30 g/mol. Pazufloxacin belongs to the quinoline carboxylic acids, a subclass of quinolines and derivatives within the organic compounds. It is classified as an organoheterocyclic compound. This compound is found in or released from healthcare, pharmaceuticals, and veterinary products as an antibiotic. Recorded exposure routes for pazufloxacin include oral and inhalation. In terms of biological activity, it acts on three recorded protein targets, serving as an inhibitor of DNA gyrase subunit A (gyrA), DNA gyrase subunit B (gyrB), and DNA topoisomerase 4 subunit A (parC). C16H15FN2O4 318.304 318.101585134 (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0⁵,¹³]trideca-5(13),6,8,11-tetraene-11-carboxylic acid pazufloxacin 127045-41-4 [H][C@]1(C)COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2C1(N)CC1 InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1 XAGMUUZPGZWTRP-ZETCQYMHSA-N Organic compounds Benzenoids Benzene and substituted derivatives N-phenylureas N-phenylureas 1,2-aminoalcohols Alkyl aryl ethers Carbonyl compounds Dialkylamines Hydrocarbon derivatives Organic oxides Organopnictogen compounds Phenol ethers Phenoxy compounds Secondary alcohols Ureas 1,2-aminoalcohol Alcohol Alkyl aryl ether Amine Aromatic homomonocyclic compound Carbonic acid derivative Carbonyl group Ether Hydrocarbon derivative N-phenylurea Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ether Phenoxy compound Secondary alcohol Secondary aliphatic amine Secondary amine Urea Aromatic homomonocyclic compounds Detected and Not Quantified logp -1 logp -0.51 ALOGPS logs -2.12 ALOGPS solubility 2.41e+00 g/l ALOGPS logp -1 ChemAxon pka_strongest_acidic 5.59 ChemAxon pka_strongest_basic 8.16 ChemAxon iupac (2S)-6-(1-aminocyclopropyl)-7-fluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.0⁵,¹³]trideca-5(13),6,8,11-tetraene-11-carboxylic acid ChemAxon average_mass 318.304 ChemAxon mono_mass 318.101585134 ChemAxon smiles [H][C@]1(C)COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2C1(N)CC1 ChemAxon formula C16H15FN2O4 ChemAxon inchi InChI=1S/C16H15FN2O4/c1-7-6-23-14-11(16(18)2-3-16)10(17)4-8-12(14)19(7)5-9(13(8)20)15(21)22/h4-5,7H,2-3,6,18H2,1H3,(H,21,22)/t7-/m0/s1 ChemAxon inchikey XAGMUUZPGZWTRP-ZETCQYMHSA-N ChemAxon polar_surface_area 92.86 ChemAxon refractivity 80.03 ChemAxon polarizability 30.76 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf84342f8> DB11774 40466872 59360 BE0008385 BE0002388 BE0000798