1.0 2016-05-22 05:57:00 UTC 2026-05-14 18:23:05 UTC Norelgestromin SmallMolecule Norelgestromin is an organic compound with the formula C21H29NO2 and an average molecular weight of 327.47 g/mol. Norelgestromin belongs to the estrane steroids, a subclass of steroids and steroid derivatives within the organic compounds. This compound is found in or released from two recorded sources: building and construction (sunshades awnings or outside screens) and healthcare, pharmaceuticals and veterinary products, specifically hormonal contraceptives for systemic use. Recorded exposure routes include transdermal and topical application. Norelgestromin interacts with three recorded protein targets, acting as an agonist, binder, or partial agonist of the progesterone receptor (PGR), albumin (ALB), and the androgen receptor (AR). C21H29NO2 327.468 327.219829178 (1S,2R,5E,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-ol Evra 53016-31-2 [H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15+/t16-,17+,18+,19-,20-,21-/m0/s1 ISHXLNHNDMZNMC-VTKCIJPMSA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Estrane steroids Estrane steroids 17-hydroxysteroids Acetylides Cyclic alcohols and derivatives Delta-4-steroids Hydrocarbon derivatives Ketoximes Organopnictogen compounds Tertiary alcohols Ynones 17-hydroxysteroid Acetylide Alcohol Aliphatic homopolycyclic compound Cyclic alcohol Delta-4-steroid Estrane-skeleton Hydrocarbon derivative Hydroxysteroid Ketoxime Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxime Tertiary alcohol Ynone Aliphatic homopolycyclic compounds Detected and Not Quantified Norelgestromin Action Pathway SMP0126539 Norelgestromin Drug Metabolism SMP0130858 Norelgestromin Drug Metabolism Action Pathway SMP0144086 logp 3.67 logp 3.18 ALOGPS logs -4.73 ALOGPS solubility 6.05e-03 g/l ALOGPS logp 3.67 ChemAxon pka_strongest_acidic 11.47 ChemAxon pka_strongest_basic 3.12 ChemAxon iupac (1S,2R,5E,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en-14-ol ChemAxon average_mass 327.468 ChemAxon mono_mass 327.219829178 ChemAxon smiles [H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O ChemAxon formula C21H29NO2 ChemAxon inchi InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15+/t16-,17+,18+,19-,20-,21-/m0/s1 ChemAxon inchikey ISHXLNHNDMZNMC-VTKCIJPMSA-N ChemAxon polar_surface_area 52.82 ChemAxon refractivity 95.85 ChemAxon polarizability 38.48 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721b7d7b40> DB06713 9568628 7843336 BE0000557 BE0000530 BE0000132