1.0 2016-05-22 06:00:27 UTC 2026-08-21 22:27:03 UTC Eletriptan SmallMolecule Eletriptan is an organic compound with the chemical formula C22H26N2O2S and an average molecular weight of 382.52 g/mol. Eletriptan belongs to the indoles, a subclass of indoles and derivatives within the organic compounds. The compound is found in or released from five recorded sources. These include healthcare, pharmaceuticals, and veterinary products specifically as analgesics, as well as electrical and electronic equipment such as electric hearing aids. Additionally, it is associated with household cleaning and consumer products, including other smoking requisites, non-electric simulated smoking devices, and tobacco product cases. The recorded route of exposure for this substance is oral. In terms of biological activity, eletriptan interacts with seven recorded protein targets. It acts as an agonist, modulator, or partial agonist of the 5-hydroxytryptamine receptor 1A (HTR1A), 5-hydroxytryptamine receptor 1B (HTR1B), 5-hydroxytryptamine receptor 1D (HTR1D), and 5-hydroxytryptamine receptor 1F (HTR1F). It is also associated with three other proteins. C22H26N2O2S 382.519 382.171498776 5-[2-(benzenesulfonyl)ethyl]-3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-1H-indole eletriptan 143322-58-1 CN1CCC[C@@H]1CC1=CNC2=C1C=C(CCS(=O)(=O)C1=CC=CC=C1)C=C2 InChI=1S/C22H26N2O2S/c1-24-12-5-6-19(24)15-18-16-23-22-10-9-17(14-21(18)22)11-13-27(25,26)20-7-3-2-4-8-20/h2-4,7-10,14,16,19,23H,5-6,11-13,15H2,1H3/t19-/m1/s1 PWVXXGRKLHYWKM-LJQANCHMSA-N Organic compounds Organoheterocyclic compounds Indoles and derivatives Indoles 3-alkylindoles Aralkylamines Azacyclic compounds Benzenesulfonyl compounds Heteroaromatic compounds Hydrocarbon derivatives N-alkylpyrrolidines Organic oxides Organopnictogen compounds Substituted pyrroles Sulfones Trialkylamines 3-alkylindole Amine Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenesulfonyl group Benzenoid Heteroaromatic compound Hydrocarbon derivative Monocyclic benzene moiety N-alkylpyrrolidine Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organopnictogen compound Organosulfur compound Pyrrole Pyrrolidine Substituted pyrrole Sulfone Sulfonyl Tertiary aliphatic amine Tertiary amine Aromatic heteropolycyclic compounds N-alkylpyrrolidine indoles sulfone Detected and Not Quantified Eletriptan Mechanism of Action Action Pathway SMP0126996 Eletriptan Drug Metabolism Action Pathway SMP0142678 Eletriptan Predicted Metabolism Pathway SMP0174576 logp 3.77 logp 3.84 ALOGPS logs -5.51 ALOGPS solubility 1.18e-03 g/l ALOGPS logp 3.77 ChemAxon pka_strongest_acidic 17.11 ChemAxon pka_strongest_basic 8.37 ChemAxon iupac 5-[2-(benzenesulfonyl)ethyl]-3-{[(2R)-1-methylpyrrolidin-2-yl]methyl}-1H-indole ChemAxon average_mass 382.519 ChemAxon mono_mass 382.171498776 ChemAxon smiles CN1CCC[C@@H]1CC1=CNC2=C1C=C(CCS(=O)(=O)C1=CC=CC=C1)C=C2 ChemAxon formula C22H26N2O2S ChemAxon inchi InChI=1S/C22H26N2O2S/c1-24-12-5-6-19(24)15-18-16-23-22-10-9-17(14-21(18)22)11-13-27(25,26)20-7-3-2-4-8-20/h2-4,7-10,14,16,19,23H,5-6,11-13,15H2,1H3/t19-/m1/s1 ChemAxon inchikey PWVXXGRKLHYWKM-LJQANCHMSA-N ChemAxon polar_surface_area 53.17 ChemAxon refractivity 110.94 ChemAxon polarizability 42.99 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72248a7260> DB00216 77993 70379 BE0000291 BE0000659 BE0000460 BE0000797 BE0000476 BE0000393 BE0000650