1.0 2016-05-22 06:30:54 UTC 2026-08-19 05:15:20 UTC Naphazoline SmallMolecule Naphazoline is an organic compound with the formula C14H14N2 and an average molecular weight of 210.28 g/mol. Naphazoline belongs to the naphthalenes, a class of benzenoids within the organic compounds. The compound is associated with 16 recorded sources across several categories. In healthcare, pharmaceuticals, and veterinary products, it is found in nasal preparations as well as decongestants and antiallergics. It is also linked to food, food processing, and cookware, specifically in food preservation, the processing of meats and fish, and the preparation of sparkling wine or wine. Within household cleaning and consumer products, it is found in tobacco smoke filters, cigar cigarettes, other smoking requisites, and non-electric simulated smoking devices. Additionally, it is released from electrical and electronic equipment, including electric switches, electric hearing aids, hybrid capacitors, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. Naphazoline acts on three recorded protein targets, serving as an agonist of the Alpha-1A adrenergic receptor (ADRA1A), the Alpha-2A adrenergic receptor (ADRA2A), and the D(2) dopamine receptor (DRD2). Recorded exposure routes for the compound include topical, ophthalmic, and nasal application. C14H14N2 210.28 210.115698459 2-[(naphthalen-2-yl)methyl]-4,5-dihydro-1H-imidazole 2-(naphthalen-2-ylmethyl)-4,5-dihydro-1H-imidazole 835-31-4 C(C1=NCCN1)C1=CC2=CC=CC=C2C=C1 InChI=1S/C14H14N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-6,9H,7-8,10H2,(H,15,16) VIXRKFBKWOHVBR-UHFFFAOYSA-N Organic compounds Benzenoids Naphthalenes Naphthalenes Azacyclic compounds Carboxamidines Carboximidamides Hydrocarbon derivatives Imidazolines Imidolactams Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds 2-imidazoline Amidine Aromatic heteropolycyclic compound Azacycle Carboximidamide Carboxylic acid amidine Hydrocarbon derivative Imidolactam Naphthalene Organic 1,3-dipolar compound Organic nitrogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Propargyl-type 1,3-dipolar organic compound Aromatic heteropolycyclic compounds Detected and Not Quantified Naphazoline Drug Metabolism Action Pathway SMP0144084 logp 2.19 logp 3.45 ALOGPS logs -3.76 ALOGPS solubility 3.68e-02 g/l ALOGPS logp 2.19 ChemAxon pka_strongest_basic 10.23 ChemAxon iupac 2-[(naphthalen-2-yl)methyl]-4,5-dihydro-1H-imidazole ChemAxon average_mass 210.28 ChemAxon mono_mass 210.115698459 ChemAxon smiles C(C1=NCCN1)C1=CC2=CC=CC=C2C=C1 ChemAxon formula C14H14N2 ChemAxon inchi InChI=1S/C14H14N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-6,9H,7-8,10H2,(H,15,16) ChemAxon inchikey VIXRKFBKWOHVBR-UHFFFAOYSA-N ChemAxon polar_surface_area 24.39 ChemAxon refractivity 65.52 ChemAxon polarizability 23.82 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7279300640> DB06711 4436 4283 BE0000501 BE0000289 BE0000756