1.0 2016-05-22 06:34:23 UTC 2026-08-19 08:29:51 UTC Luliconazole SmallMolecule Luliconazole is an organic compound with the formula C14H9Cl2N3S2 and an average molecular weight of 354.27 g/mol. Luliconazole belongs to the halobenzenes, a subclass of benzene and substituted derivatives within the organic compounds. It is used in healthcare, pharmaceuticals, and veterinary products as an antifungal for dermatological use, with topical application as the recorded exposure route. Mechanistically, it acts as an inhibitor of the protein target Lanosterol 14-alpha demethylase (ERG11). C14H9Cl2N3S2 354.27 352.961495 2-[(2E,4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile luliconazole 187164-19-8 ClC1=CC(Cl)=C(C=C1)[C@@H]1CS\C(S1)=C(\C#N)N1C=CN=C1 InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1 YTAOBBFIOAEMLL-REQDGWNSSA-N Organic compounds Benzenoids Benzene and substituted derivatives Halobenzenes Dichlorobenzenes 1,3-dithiolanes Aryl chlorides Azacyclic compounds Heteroaromatic compounds Hydrocarbon derivatives N-substituted imidazoles Nitriles Organochlorides Organopnictogen compounds 1,3-dichlorobenzene 1,3-dithiolane Aromatic heteromonocyclic compound Aryl chloride Aryl halide Azacycle Azole Carbonitrile Dithiolane Heteroaromatic compound Hydrocarbon derivative Imidazole N-substituted imidazole Nitrile Organic nitrogen compound Organochloride Organohalogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Aromatic heteromonocyclic compounds dichlorobenzene Detected and Not Quantified Luliconazole Action Pathway SMP0125821 Luliconazole Drug Metabolism SMP0130740 Luliconazole Drug Metabolism Action Pathway SMP0144227 logp 4.07 logp 4.27 ALOGPS logs -3.73 ALOGPS solubility 6.59e-02 g/l ALOGPS logp 4.07 ChemAxon pka_strongest_basic 6.34 ChemAxon iupac 2-[(2E,4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-(1H-imidazol-1-yl)acetonitrile ChemAxon average_mass 354.27 ChemAxon mono_mass 352.961495 ChemAxon smiles ClC1=CC(Cl)=C(C=C1)[C@@H]1CS\C(S1)=C(\C#N)N1C=CN=C1 ChemAxon formula C14H9Cl2N3S2 ChemAxon inchi InChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1 ChemAxon inchikey YTAOBBFIOAEMLL-REQDGWNSSA-N ChemAxon polar_surface_area 41.61 ChemAxon refractivity 101 ChemAxon polarizability 33.65 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72248219a8> DB08933 3003141 BE0000233