1.0 2016-05-22 06:39:17 UTC 2026-08-22 08:31:18 UTC Beclazone SmallMolecule Beclazone belongs to the pregnane steroids, a subclass of steroids and steroid derivatives within the organic compounds. With an average molecular weight of 521.04 g/mol, Beclazone is a heavy molecule. Its chemical formula is C28H37ClO7. The compound is found in or released from 33 recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is used as an intestinal antiinflammatory agent, as a corticosteroid, in corticosteroid combinations with antibiotics, in nasal preparations, and as a drug for obstructive airway diseases. Other recorded sources include electrical and electronic equipment, such as amplifiers, antennas, auxiliary devices, discharge lamps, and electric switches. It is also associated with building and construction materials, specifically roofs, stairs, and ramps. In the realm of food, food processing, and cookware, it is linked to the processing of meats and fish, as well as the preparation of wort, wine or sparkling wine, and fermentation processes for beer. Additionally, it is found in household cleaning and consumer products, including pipe accessories, tobacco smoke filters, cigar cigarettes, and non-electric simulated smoking devices. Recorded exposure routes for Beclazone include topical, nasal, and respiratory pathways. Beclazone interacts with four recorded protein targets. It acts as an agonist or modulator of the glucocorticoid receptor (NR3C1) and targets steroid hormone receptors ERR1 (ESRRA) and ERR2 (ESRRB), as well as the estrogen-related receptor gamma (ESRRG). Human Neurotoxin Beclometasone dipropionate Beclomethasondipropionat C28H37ClO7 521.042 520.222781245 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate beconase 5534-09-8 [H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 KUVIULQEHSCUHY-XYWKZLDCSA-N Organic compounds Lipids and lipid-like molecules Steroids and steroid derivatives Pregnane steroids Gluco/mineralocorticoids, progestogins and derivatives 11-beta-hydroxysteroids 20-oxosteroids 3-oxo delta-1,4-steroids Alkyl chlorides Alpha-acyloxy ketones Carboxylic acid esters Chlorohydrins Cyclic alcohols and derivatives Cyclic ketones Delta-1,4-steroids Dicarboxylic acids and derivatives Halogenated steroids Hydrocarbon derivatives Organic oxides Organochlorides Secondary alcohols Steroid esters 11-beta-hydroxysteroid 11-hydroxysteroid 20-oxosteroid 3-oxo-delta-1,4-steroid 3-oxosteroid 9-halo-steroid Alcohol Aliphatic homopolycyclic compound Alkyl chloride Alkyl halide Alpha-acyloxy ketone Carbonyl group Carboxylic acid derivative Carboxylic acid ester Chlorohydrin Cyclic alcohol Cyclic ketone Delta-1,4-steroid Dicarboxylic acid or derivatives Halo-steroid Halohydrin Hydrocarbon derivative Hydroxysteroid Ketone Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organooxygen compound Oxosteroid Progestogin-skeleton Secondary alcohol Steroid ester Aliphatic homopolycyclic compounds 11beta-hydroxy steroid 20-oxo steroid 3-oxo-Delta(1),Delta(4)-steroid chlorinated steroid corticosteroid enone glucocorticoid propanoate ester steroid ester Detected and Not Quantified Beclomethasone dipropionate Action Pathway SMP0126172 Beclometasone dipropionate Drug Metabolism Pathway SMP0145319 logp 4.43 logp 3.69 ALOGPS logs -5.40 ALOGPS solubility 2.08e-03 g/l ALOGPS logp 4.43 ChemAxon pka_strongest_acidic 13.85 ChemAxon pka_strongest_basic -3.3 ChemAxon iupac 2-[(1R,2S,10S,11S,13S,14R,15S,17S)-1-chloro-17-hydroxy-2,13,15-trimethyl-5-oxo-14-(propanoyloxy)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-14-yl]-2-oxoethyl propanoate ChemAxon average_mass 521.042 ChemAxon mono_mass 520.222781245 ChemAxon smiles [H][C@@]12C[C@H](C)[C@](OC(=O)CC)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C ChemAxon formula C28H37ClO7 ChemAxon inchi InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 ChemAxon inchikey KUVIULQEHSCUHY-XYWKZLDCSA-N ChemAxon polar_surface_area 106.97 ChemAxon refractivity 134.79 ChemAxon polarizability 54.41 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bbfa8fc80> DB00394 21700 20396 BE0000794 BE0003722 BE0005001 BE0002088