1.0 2016-05-22 06:58:25 UTC 2026-08-19 06:31:18 UTC Stiripentol SmallMolecule Stiripentol is an organic compound with the formula C14H18O3 and an average molecular weight of 234.29 g/mol. Stiripentol belongs to the benzodioxoles, a class of organoheterocyclic compounds within the organic compounds. The compound is found in or released from two recorded sources: healthcare, pharmaceuticals & veterinary products (specifically antiepileptics) and household cleaning & consumer products (specifically non electric simulated smoking devices). The recorded exposure route for this substance is oral. Stiripentol interacts with 18 recorded protein targets. It acts as an agonist and a positive allosteric modulator, inhibitor, or modulator of the Gamma-aminobutyric acid receptor subunit pi (GABRP), Gamma-aminobutyric acid receptor subunit delta (GABRD), Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1), and Gamma-aminobutyric acid receptor subunit beta-1 (GABRB1). Additionally, it is associated with 14 other proteins. C14H18O3 234.295 234.12559444 (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol stiripentol 49763-96-4 CC(C)(C)C(O)\C=C\C1=CC2=C(OCO2)C=C1 InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+ IBLNKMRFIPWSOY-FNORWQNLSA-N Organic compounds Organoheterocyclic compounds Benzodioxoles Benzodioxoles Acetals Hydrocarbon derivatives Oxacyclic compounds Secondary alcohols Styrenes Acetal Alcohol Aromatic heteropolycyclic compound Benzenoid Benzodioxole Hydrocarbon derivative Organic oxygen compound Organooxygen compound Oxacycle Secondary alcohol Styrene Aromatic heteropolycyclic compounds Detected and Not Quantified Stiripentol GABA(A) Antiepileptic Action Pathway SMP0126168 Stiripentol Drug Metabolism SMP0130741 Stiripentol Drug Metabolism Action Pathway SMP0144322 logp 3.12 logp 3.01 ALOGPS logs -2.76 ALOGPS solubility 4.05e-01 g/l ALOGPS logp 3.12 ChemAxon pka_strongest_acidic 14.34 ChemAxon pka_strongest_basic -3.1 ChemAxon iupac (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol ChemAxon average_mass 234.295 ChemAxon mono_mass 234.12559444 ChemAxon smiles CC(C)(C)C(O)\C=C\C1=CC2=C(OCO2)C=C1 ChemAxon formula C14H18O3 ChemAxon inchi InChI=1S/C14H18O3/c1-14(2,3)13(15)7-5-10-4-6-11-12(8-10)17-9-16-11/h4-8,13,15H,9H2,1-3H3/b7-5+ ChemAxon inchikey IBLNKMRFIPWSOY-FNORWQNLSA-N ChemAxon polar_surface_area 38.69 ChemAxon refractivity 66.77 ChemAxon polarizability 26.21 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72264287a0> DB09118 5311454 4470940 BE0003596 BE0003599 BE0000795 BE0002344 BE0003592 BE0002345 BE0000471 BE0000523 BE0000381 BE0002346 BE0000478 BE0003595 BE0000764 BE0003593 BE0003594 BE0003597 BE0000425 BE0000068