1.0 2016-05-22 07:18:33 UTC 2026-08-19 01:25:33 UTC Lacosamide SmallMolecule Lacosamide is an organic compound with the chemical formula C13H18N2O3 and an average molecular weight of 250.29 g/mol. Lacosamide belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. This compound is identified as being found in or released from one recorded source: healthcare, pharmaceuticals & veterinary products, specifically as an antiepileptic. Recorded exposure routes for the substance include oral and intravenous administration. Lacosamide interacts with five recorded protein targets. It acts as a blocker, inhibitor, or modulator of sodium channel protein type 3 subunit alpha (SCN3A), sodium channel protein type 9 subunit alpha (SCN9A), and sodium channel protein type 10 subunit alpha (SCN10A). Additionally, it targets dihydropyrimidinase-related protein 2 (DPYSL2) and one other protein. Human Neurotoxin C13H18N2O3 250.2936 250.131742452 (2R)-N-benzyl-2-acetamido-3-methoxypropanamide lacosamide 175481-36-4 COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1 InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1 VPPJLAIAVCUEMN-GFCCVEGCSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues N-acyl-alpha amino acids and derivatives Acetamides Alpha amino acid amides Benzene and substituted derivatives Carbonyl compounds Dialkyl ethers Hydrocarbon derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Secondary carboxylic acid amides Acetamide Alpha-amino acid amide Aromatic homomonocyclic compound Benzenoid Carbonyl group Carboxamide group Dialkyl ether Ether Hydrocarbon derivative Monocyclic benzene moiety N-acyl-alpha amino acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Secondary carboxylic acid amide Aromatic homomonocyclic compounds Detected and Not Quantified Lacosamide Action Pathway SMP0126276 Lacosamide Drug Metabolism Action Pathway SMP0144018 logp -0.022 logp 0.18 ALOGPS logs -2.73 ALOGPS solubility 4.65e-01 g/l ALOGPS logp -0.022 ChemAxon pka_strongest_acidic 12.47 ChemAxon pka_strongest_basic -1.5 ChemAxon iupac (2R)-N-benzyl-2-acetamido-3-methoxypropanamide ChemAxon average_mass 250.2936 ChemAxon mono_mass 250.131742452 ChemAxon smiles COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1 ChemAxon formula C13H18N2O3 ChemAxon inchi InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1 ChemAxon inchikey VPPJLAIAVCUEMN-GFCCVEGCSA-N ChemAxon polar_surface_area 67.43 ChemAxon refractivity 67.57 ChemAxon polarizability 26.68 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb3c16ce0> DB06218 21634109 10266281 BE0001143 BE0002082 BE0000177 BE0005806 BE0000192