1.0 2016-05-22 07:21:21 UTC 2026-05-14 18:18:46 UTC Rivaroxaban SmallMolecule Rivaroxaban is an organic compound with the formula C19H18ClN3O5S and an average molecular weight of 435.88 g/mol. Rivaroxaban belongs to the morpholines, a subclass of oxazinanes within the organic compounds. It is classified as an organoheterocyclic compound. This substance acts as an antagonist of coagulation factor X (F10). Rivaroxaban is found in or released from healthcare, pharmaceuticals, and veterinary products as an antithrombotic agent, with oral exposure as the recorded route. Human Neurotoxin C19H18ClN3O5S 435.88 435.0655696 5-chloro-N-({2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide rivaroxaban 366789-02-8 ClC1=CC=C(S1)C(=O)NCC1CN(C(=O)O1)C1=CC=C(C=C1)N1CCOCC1=O InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25) KGFYHTZWPPHNLQ-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Oxazinanes Morpholines Phenylmorpholines 2,5-disubstituted thiophenes 2-heteroaryl carboxamides Aryl chlorides Azacyclic compounds Benzene and substituted derivatives Carbamate esters Carbonyl compounds Dialkyl ethers Heteroaromatic compounds Hydrocarbon derivatives Lactams Organic carbonic acids and derivatives Organic oxides Organochlorides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Oxazolidinones Secondary carboxylic acid amides Tertiary carboxylic acid amides Thiophene carboxamides 2,5-disubstituted thiophene 2-heteroaryl carboxamide Aromatic heteromonocyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Carbamic acid ester Carbonic acid derivative Carbonyl group Carboxamide group Carboxylic acid derivative Dialkyl ether Ether Heteroaromatic compound Hydrocarbon derivative Lactam Monocyclic benzene moiety Organic nitrogen compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Oxazolidine Oxazolidinone Phenylmorpholine Secondary carboxylic acid amide Tertiary carboxylic acid amide Thiophene Thiophene carboxamide Thiophene carboxylic acid or derivatives Aromatic heteromonocyclic compounds Detected and Not Quantified logp 1.9 logp 1.74 ALOGPS logs -4.64 ALOGPS solubility 1.00e-02 g/l ALOGPS logp 1.9 ChemAxon pka_strongest_acidic 13.6 ChemAxon pka_strongest_basic -1.6 ChemAxon iupac 5-chloro-N-({2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide ChemAxon average_mass 435.88 ChemAxon mono_mass 435.0655696 ChemAxon smiles ClC1=CC=C(S1)C(=O)NCC1CN(C(=O)O1)C1=CC=C(C=C1)N1CCOCC1=O ChemAxon formula C19H18ClN3O5S ChemAxon inchi InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25) ChemAxon inchikey KGFYHTZWPPHNLQ-UHFFFAOYSA-N ChemAxon polar_surface_area 88.18 ChemAxon refractivity 104.74 ChemAxon polarizability 43.82 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7279b13f30> DB06228 6433119 4938307 BE0000216