1.0 2016-05-25 02:49:15 UTC 2026-05-14 18:09:05 UTC Arachidonic acid SmallMolecule Arachidonic acid belongs to the fatty acids and conjugates, a subclass of fatty acyls within the organic compounds. This lipid-like molecule has the chemical formula C20H32O2 and an average molecular weight of 304.47 g/mol. Industrially, the compound is utilized as a conditioner and softener. The substance is released from plastics, specifically polystyrene and polypropylene. It has been recorded in three distinct sources: antennas within electrical and electronic equipment, food contact materials used in food processing and cookware, and indoor air, dust, and atmospheric transport. Exposure to arachidonic acid can occur through oral, inhalation, and touch routes. At the molecular level, arachidonic acid interacts with five recorded protein targets. It serves as a ligand or inhibitor for Prostaglandin G/H synthase 1 (PTGS1), the 14 kDa fatty acid-binding protein, the bile acid receptor (NR1H4), and the peroxisome proliferator-activated receptor alpha (PPARA), in addition to one other protein. Human Neurotoxin C20H32O2 304.4669 304.240230268 (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid arachidonic acid 506-32-1 CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- YZXBAPSDXZZRGB-DOFZRALJSA-N Organic compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Long-chain fatty acids Carbonyl compounds Carboxylic acids Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Straight chain fatty acids Unsaturated fatty acids Aliphatic acyclic compound Carbonyl group Carboxylic acid Carboxylic acid derivative Hydrocarbon derivative Long-chain fatty acid Monocarboxylic acid or derivatives Organic oxide Organic oxygen compound Organooxygen compound Straight chain fatty acid Unsaturated fatty acid Aliphatic acyclic compounds Polyunsaturated fatty acids Unsaturated fatty acids Unsaturated fatty acids icosa-5,8,11,14-tetraenoic acid long-chain fatty acid omega-6 fatty acid Detected and Not Quantified Alpha Linolenic Acid and Linoleic Acid Metabolism SMP0000018 Arachidonic Acid Metabolism SMP0000075 Leukotriene C4 Synthesis Deficiency SMP0000353 Piroxicam Action Pathway SMP0000077 Acetylsalicylic Acid Action Pathway SMP0000083 Etodolac Action Pathway SMP0000084 Ketoprofen Action Pathway SMP0000085 Ibuprofen Action Pathway SMP0000086 Rofecoxib Action Pathway SMP0000087 Diclofenac Action Pathway SMP0000093 Sulindac Action Pathway SMP0000094 Celecoxib metabolism Pathway SMP0000096 Ketorolac Action Pathway SMP0000098 Suprofen Action Pathway SMP0000101 Bromfenac Action Pathway SMP0000102 Indomethacin Action Pathway SMP0000104 Mefenamic Acid Action Pathway SMP0000109 Oxaprozin Action Pathway SMP0000113 Nabumetone Action Pathway SMP0000114 Naproxen Action Pathway SMP0000120 Diflunisal Action Pathway SMP0000289 Meloxicam Action Pathway SMP0000106 Valdecoxib Action Pathway SMP0000116 Fc Epsilon Receptor I Signaling in Mast Cells SMP0000358 Antipyrine Action Pathway SMP0000692 Antrafenine Action Pathway SMP0000693 Carprofen Action Pathway SMP0000694 Etoricoxib Action Pathway SMP0000695 Fenoprofen Action Pathway SMP0000696 Flurbiprofen Action Pathway SMP0000697 Magnesium Salicylate Action Pathway SMP0000698 Lumiracoxib Action Pathway SMP0000699 Lornoxicam Action Pathway SMP0000700 Phenylbutazone Action Pathway SMP0000701 Nepafenac Action Pathway SMP0000702 Trisalicylate-Choline Action Pathway SMP0000703 Tolmetin Action Pathway SMP0000704 Tiaprofenic Acid Action Pathway SMP0000705 Tenoxicam Action Pathway SMP0000706 Salsalate Action Pathway SMP0000707 Salicylate-Sodium Action Pathway SMP0000708 Salicylic Acid Action Pathway SMP0000709 Acetaminophen Action Pathway SMP0000710 GnRH Signaling Pathway SMP0063811 Prednisolone Action Action Pathway New SMP0122639 Dipyridamole Action Pathway SMP0122804 Acetaminophen Action Pathway (New) SMP0122823 Etoricoxib Action Pathway (New) SMP0122862 Lumiracoxib NSAID Action Pathway SMP0124453 Valdecoxib Action Pathway (New) SMP0124454 Antrafenine Anti-inflammatory Action Pathway SMP0124549 Carprofen NSAID Action Pathway SMP0124580 Nepafenac NSAID Action Pathway SMP0124581 Suprofen NSAID Action Pathway SMP0124582 Mefenamic Acid NSAID Action Pathway SMP0124586 Lornoxicam NSAID Action Pathway SMP0124587 Piroxicam NSAID Action Pathway SMP0124588 Tenoxicam Action Pathway (New) SMP0124589 Salicylic Acid COX Action Pathway SMP0124590 Indomethacin NSAID Action Pathway SMP0124592 Nabumetone NSAID Action Pathway SMP0124604 Tolmetin Action Pathway (New) SMP0124606 Tiaprofenic Acid Action Pathway (New) SMP0124607 Meloxicam NSAID Action Pathway SMP0124609 Fenoprofen Anti-inflammatory Action Pathway SMP0124610 Ibuprofen NSAID Action Pathway SMP0124611 Naproxen NSAID Action Pathway SMP0124612 Oxaprozin NSAID Action Pathway SMP0124613 Etodolac Action Pathway (New) SMP0124626 Ketorolac NSAID Action Pathway SMP0124627 Acetylsalicylic Acid Action Pathway (New) SMP0124628 Magnesium Salicylate NSAID Action Pathway SMP0124629 Salicylate-Sodium NSAID Action Pathway SMP0124630 Diflunisal NSAID Action Pathway SMP0124631 Antipyrine NSAID Action Pathway SMP0124632 Diclofenac NSAID Action Pathway SMP0124633 Flurbiprofen NSAID Action Pathway SMP0124634 Ketoprofen NSAID Action Pathway SMP0124635 Succinate Immunometabolism Pathway SMP0124909 Trisalicylate-Choline Action Pathway (New) SMP0124989 Aceclofenac Action Pathway SMP0124997 Prednisone Anti-inflammatory Action Pathway SMP0125039 Acemetacin Action Pathway SMP0126084 Mesalazine Action Pathway SMP0126087 Trolamine salicylate Action Pathway SMP0126096 Loxoprofen Action Pathway SMP0126099 Meclofenamic acid Action Pathway SMP0126104 Balsalazide Action Pathway SMP0126108 Olsalazine Action Pathway SMP0126110 Dexibuprofen Action Pathway SMP0126112 Dexketoprofen Action Pathway SMP0126113 Sulfasalazine Action Pathway SMP0126115 Alclometasone Action Pathway SMP0126158 Amcinonide Action Pathway SMP0126169 Beclomethasone dipropionate Action Pathway SMP0126172 Betamethasone Action Pathway SMP0126176 Betamethasone phosphate Action Pathway SMP0126180 Budesonide Action Pathway SMP0126182 Ciclesonide Action Pathway SMP0126184 Clobetasol propionate Action Pathway SMP0126191 Clobetasone Action Pathway SMP0126192 Clocortolone Action Pathway SMP0126193 Cortisone Acetate Action Pathway SMP0126207 Deflazacort Action Pathway SMP0126212 Desonide Action Pathway SMP0126223 Desoximetasone Action Pathway SMP0126224 Dexamethasone Action Pathway SMP0126226 Diflorasone Action Pathway SMP0126227 Flumethasone Action Pathway SMP0126233 Fluocinonide Action Pathway SMP0126234 Flurandrenolide Action Pathway SMP0126235 Methyl Prednisolone Action Pathway SMP0126236 Hydrocortamate Action Pathway SMP0126237 Prednicarbate Action Pathway SMP0126238 Ulobetasol Action Pathway SMP0126240 Fluocinolone acetonide Action Pathway SMP0126241 Fluticasone Action Pathway SMP0126244 Prednisolone Phosphate Action Pathway SMP0126245 Prednisolone acetate MOA Action Pathway SMP0126246 Fluticasone furoate Action Pathway SMP0126248 Fluticasone propionate Action Pathway SMP0126249 Hydrocortisone Action Pathway SMP0126250 Triamcinolone Action Pathway SMP0126251 Flunisolide Action Pathway SMP0126252 Rimexolone Action Pathway SMP0126253 Difluprednate Action Pathway SMP0126254 Fluorometholone Action Pathway SMP0126255 Medrysone Action Pathway SMP0126256 Loteprednol etabonate Action Pathway SMP0126258 Bromfenac NSAID Action Pathway SMP0126376 Parecoxib Action Pathway SMP0126380 Celecoxib Action Pathway (New) SMP0126384 Dipyridamole Phosphodiesterase Action Pathway SMP0126489 Phenylbutazone Action Pathway (New) SMP0126545 Triflusal Action Pathway (new) SMP0126547 Triflusal Action Pathway SMP0126548 Tolfenamic acid Action Pathway SMP0126549 Glycol salicylate Action Pathway SMP0126550 Menthyl salicylate Action Pathway SMP0126552 Sulindac Action Pathway (New) SMP0126555 Icosapent Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway SMP0126557 Fish oil Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway SMP0126563 Salsalate Action Pathway (New) SMP0126583 Prostaglandin SMP0127682 Regulation of Lipolysis SMP0573273 Ferroptosis SMP0575898 logp 6.59 logp 6.80 ALOGPS logs -6.30 ALOGPS solubility 1.51e-04 g/l ALOGPS logp 6.59 ChemAxon pka_strongest_acidic 4.82 ChemAxon iupac (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid ChemAxon average_mass 304.4669 ChemAxon mono_mass 304.240230268 ChemAxon smiles CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O ChemAxon formula C20H32O2 ChemAxon inchi InChI=1S/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15- ChemAxon inchikey YZXBAPSDXZZRGB-DOFZRALJSA-N ChemAxon polar_surface_area 37.3 ChemAxon refractivity 99.95 ChemAxon polarizability 37.2 ChemAxon rotatable_bond_count 14 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb3e57770> DB04557 5312542 4471967 BE0000017 BE0001566 BE0000071 BE0001777 BE0000412