1.0 2016-05-25 02:53:11 UTC 2026-04-14 17:04:02 UTC Ferulic acid SmallMolecule Ferulic acid (C10H10O4) is a compound with an average molecular weight of 194.18 g/mol. Ferulic acid belongs to the hydroxycinnamic acids and derivatives, a subclass of cinnamic acids and derivatives within the organic compounds. It is categorized under the superclass of phenylpropanoids and polyketides. The compound serves as an industrial additive (PMC10048273) and acts as an antioxidant for both industrial and biological applications (PMC10048273, PMC10224177, PMC10573426, PMC12562121, PMC3595371, PMC9607127, PMC9786992, PMC8253632). Ferulic acid has been recorded in 11 sources, including building and construction ceilings, electrical and electronic equipment coils, and household cleaning and consumer products such as soap dispensers. It is also found in food, food processing, and cookware, specifically in the preparation of vinegar, wort, malt, wine or sparkling wine, and molasses and the treatment of molasses. Biologically, ferulic acid targets 12 proteins, acting as an inhibitor of O-methyltransferase, Est1e, Endo-1,4-beta-xylanase Z (xynZ), and Endo-1,4-beta-xylanase Y (xynY). The compound is used as a treatment for skin cancer (PMC3595371) and exhibits therapeutic effects on cancer (PMC9786992), ischemic stroke (PMC8253632), inflammation (PMC13316579), and depression (PMC10831359). ferulate trans-Ferulic acid C10H10O4 194.184 194.057908808 (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid ferulic acid 537-98-4 COC1=C(O)C=CC(\C=C\C(O)=O)=C1 InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ KSEBMYQBYZTDHS-HWKANZROSA-N Organic compounds Phenylpropanoids and polyketides Cinnamic acids and derivatives Hydroxycinnamic acids and derivatives Hydroxycinnamic acids 1-hydroxy-2-unsubstituted benzenoids Alkyl aryl ethers Anisoles Carbonyl compounds Carboxylic acids Cinnamic acids Coumaric acids and derivatives Hydrocarbon derivatives Methoxybenzenes Methoxyphenols Monocarboxylic acids and derivatives Organic oxides Phenoxy compounds Styrenes 1-hydroxy-2-unsubstituted benzenoid Alkyl aryl ether Anisole Aromatic homomonocyclic compound Benzenoid Carbonyl group Carboxylic acid Carboxylic acid derivative Cinnamic acid Coumaric acid or derivatives Ether Hydrocarbon derivative Hydroxycinnamic acid Methoxybenzene Methoxyphenol Monocarboxylic acid or derivatives Monocyclic benzene moiety Organic oxide Organic oxygen compound Organooxygen compound Phenol Phenol ether Phenoxy compound Styrene Aromatic homomonocyclic compounds Coniferyl alcohol derivatives ferulic acids Detected and Not Quantified logp 1.58 ALOGPS logs -2.33 ALOGPS solubility 9.06e-01 g/l ALOGPS logp 1.67 ChemAxon pka_strongest_acidic 3.77 ChemAxon pka_strongest_basic -4.9 ChemAxon iupac (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid ChemAxon average_mass 194.184 ChemAxon mono_mass 194.057908808 ChemAxon smiles COC1=C(O)C=CC(\C=C\C(O)=O)=C1 ChemAxon formula C10H10O4 ChemAxon inchi InChI=1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+ ChemAxon inchikey KSEBMYQBYZTDHS-HWKANZROSA-N ChemAxon polar_surface_area 66.76 ChemAxon refractivity 51.5 ChemAxon polarizability 19.18 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7224128840> DB07767 445858 BE0003007 BE0004078 BE0004079 BE0003784 BE0001653 BE0000322 BE0003634 BE0002437 BE0003628 BE0000267 BE0000535 BE0002196