1.0 2016-05-25 02:54:43 UTC 2026-05-14 18:59:49 UTC Hyaluronic acid SmallMolecule Hyaluronic acid belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. With an average molecular weight of 776.65 g/mol, Hyaluronic acid is a heavy molecule. It has the chemical formula C28H44N2O23. In industrial applications, the compound is used as a humectant, an anti-static agent, and a softener and conditioner. The compound is found in or released from ten recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is utilized in surgical aids, nasal preparations, drugs for disorders of the musculo-skeletal system, and cicatrizants. It is also present in household cleaning and consumer products, specifically soap dispensers, other smoking requisites, and non-electric simulated smoking devices. Additionally, it is found in communication cables or conductors within electrical and electronic equipment, and in the preparation of wine or sparkling wine and the preparation of vinegar. Recorded exposure routes include oral, topical, dental, vaginal, cutaneous, intra-articular, and intraepidermal. Hyaluronic acid interacts with 15 recorded protein targets. It acts as a binder/inhibitor and a binder/modulator of the CD44 antigen, the hyaluronan mediated motility receptor (HMMR), the intercellular adhesion molecule 1 (ICAM1), and the neurocan core protein (NCAN), as well as 11 other proteins. C28H44N2O23 776.651 776.233485685 (2S,4S,5R,6S)-6-{[(2S,3R,5S,6R)-2-{[(3S,4R,5R,6R)-2-carboxy-6-{[(3R,4R,5S,6R)-2,5-dihydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxan-3-yl]oxy}-5-hydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid (2S,4S,5R,6S)-6-{[(2S,3R,5S,6R)-2-{[(3S,4R,5R,6R)-2-carboxy-6-{[(3R,4R,5S,6R)-2,5-dihydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxan-3-yl]oxy}-5-hydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid 9004-61-9 [H]C1(O)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O[C@]2([H])OC([H])(C(O)=O)[C@@]([H])(O[C@]3([H])O[C@]([H])(CO)[C@@]([H])(O)C([H])(O[C@@]4([H])O[C@]([H])(C(O)=O)C([H])(O)[C@]([H])(O)[C@@]4([H])O)[C@@]3([H])N=C(C)O)[C@]([H])(O)[C@@]2([H])O)[C@@]1([H])N=C(C)O InChI=1S/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14?,15-,16-,17-,18-,19?,20+,21+,22?,25?,26+,27+,28-/m1/s1 KIUKXJAPPMFGSW-YXBJCWEESA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Acylaminosugars Acetals Acetamides Beta hydroxy acids and derivatives Carbonyl compounds Carboxylic acids Dicarboxylic acids and derivatives Fatty acyl glycosides Hemiacetals Hydrocarbon derivatives N-acyl-alpha-hexosamines O-glucuronides O-glycosyl compounds Oligosaccharides Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Oxanes Polyols Primary alcohols Pyrans Secondary alcohols Secondary carboxylic acid amides 1-o-glucuronide Acetal Acetamide Acylaminosugar Alcohol Aliphatic heteromonocyclic compound Beta-hydroxy acid Carbonyl group Carboxamide group Carboxylic acid Carboxylic acid derivative Dicarboxylic acid or derivatives Fatty acyl Fatty acyl glycoside Glucuronic acid or derivatives Glycosyl compound Hemiacetal Hydrocarbon derivative Hydroxy acid N-acyl-alpha-hexosamine O-glucuronide O-glycosyl compound Oligosaccharide Organic nitrogen compound Organic oxide Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Oxane Polyol Primary alcohol Pyran Secondary alcohol Secondary carboxylic acid amide Aliphatic heteromonocyclic compounds Detected and Not Quantified Hyaluronic acid Drug Metabolism SMP0130655 Hyaluronic acid Drug Metabolism Action Pathway SMP0144174 logp -8.2 logp -1.51 ALOGPS logs -1.20 ALOGPS solubility 4.93e+01 g/l ALOGPS logp -6.5 ChemAxon pka_strongest_acidic 2.82 ChemAxon pka_strongest_basic -3.9 ChemAxon iupac (2S,4S,5R,6S)-6-{[(2S,3R,5S,6R)-2-{[(3S,4R,5R,6R)-2-carboxy-6-{[(3R,4R,5S,6R)-2,5-dihydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxan-3-yl]oxy}-5-hydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-4-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid ChemAxon average_mass 776.651 ChemAxon mono_mass 776.233485685 ChemAxon smiles [H]C1(O)O[C@]([H])(CO)[C@@]([H])(O)[C@]([H])(O[C@]2([H])OC([H])(C(O)=O)[C@@]([H])(O[C@]3([H])O[C@]([H])(CO)[C@@]([H])(O)C([H])(O[C@@]4([H])O[C@]([H])(C(O)=O)C([H])(O)[C@]([H])(O)[C@@]4([H])O)[C@@]3([H])N=C(C)O)[C@]([H])(O)[C@@]2([H])O)[C@@]1([H])N=C(C)O ChemAxon formula C28H44N2O23 ChemAxon inchi InChI=1S/C28H44N2O23/c1-5(33)29-9-18(11(35)7(3-31)47-25(9)46)49-28-17(41)15(39)20(22(53-28)24(44)45)51-26-10(30-6(2)34)19(12(36)8(4-32)48-26)50-27-16(40)13(37)14(38)21(52-27)23(42)43/h7-22,25-28,31-32,35-41,46H,3-4H2,1-2H3,(H,29,33)(H,30,34)(H,42,43)(H,44,45)/t7-,8-,9-,10-,11-,12-,13+,14?,15-,16-,17-,18-,19?,20+,21+,22?,25?,26+,27+,28-/m1/s1 ChemAxon inchikey KIUKXJAPPMFGSW-YXBJCWEESA-N ChemAxon polar_surface_area 406.69 ChemAxon refractivity 156.14 ChemAxon polarizability 69.68 ChemAxon rotatable_bond_count 12 ChemAxon acceptor_count 25 ChemAxon donor_count 14 ChemAxon physiological_charge -2 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7276bf9740> DB08818 3084050 2341173 BE0001113 BE0001085 BE0004702 BE0004512 BE0004606 BE0004930 BE0004933 BE0004935 BE0004940 BE0004944 BE0004948 BE0004952 BE0004942 BE0004943 BE0010044