1.0 2016-05-25 03:25:14 UTC 2026-05-14 16:24:28 UTC Pravastatin SmallMolecule Pravastatin is an organic compound with the formula C23H36O7 and an average molecular weight of 424.53 g/mol. Pravastatin belongs to the medium-chain hydroxy acids and derivatives, a subclass of hydroxy acids and derivatives within the organic compounds. It is recorded as a biological antioxidant (PMC8252743). The compound is identified as a lipid modifying agent within healthcare, pharmaceuticals, and veterinary products. It has two recorded protein targets, acting as an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) and Histone deacetylase 2 (HDAC2). The oral route is the recorded exposure route for this substance. Pravastatin is found in or released from 13 recorded sources. These include drinking water and water supply (Drinking water), as well as food, food processing and cookware sources such as the preparation of malt, the preparation of wort, the preparation of wine or sparkling wine, and fermentation processes for beer. Within household cleaning and consumer products, it is associated with cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. Additionally, it is found in electrical and electronic equipment, specifically antennas, amplifiers, television systems, and electrically stimulated smoking devices. C23H36O7 424.5277 424.246103506 (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid pravastatin 81093-37-0 [H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 TUZYXOIXSAXUGO-PZAWKZKUSA-N Organic compounds Organic acids and derivatives Hydroxy acids and derivatives Medium-chain hydroxy acids and derivatives Medium-chain hydroxy acids and derivatives Beta hydroxy acids and derivatives Branched fatty acids Carbonyl compounds Carboxylic acid esters Carboxylic acids Dicarboxylic acids and derivatives Fatty acid esters Fatty alcohols Hydrocarbon derivatives Hydroxy fatty acids Medium-chain fatty acids Organic oxides Secondary alcohols Alcohol Aliphatic homopolycyclic compound Beta-hydroxy acid Branched fatty acid Carbonyl group Carboxylic acid Carboxylic acid derivative Carboxylic acid ester Dicarboxylic acid or derivatives Fatty acid ester Fatty acyl Fatty alcohol Hydrocarbon derivative Hydroxy fatty acid Medium-chain fatty acid Medium-chain hydroxy acid Organic oxide Organic oxygen compound Organooxygen compound Secondary alcohol Aliphatic homopolycyclic compounds 3-hydroxy carboxylic acid carbobicyclic compound carboxylic ester hydroxy monocarboxylic acid secondary alcohol statin (semi-synthetic) Detected and Not Quantified Pravastatin Action Pathway SMP0000089 Pravastatin Action Pathway (New) SMP0124576 Pravastatin Drug Metabolism Action Pathway SMP0142638 logp 1.65 logp 2.23 ALOGPS logs -3.24 ALOGPS solubility 2.42e-01 g/l ALOGPS logp 1.65 ChemAxon pka_strongest_acidic 4.21 ChemAxon pka_strongest_basic -2.7 ChemAxon iupac (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid ChemAxon average_mass 424.5277 ChemAxon mono_mass 424.246103506 ChemAxon smiles [H][C@]12[C@H](C[C@H](O)C=C1C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC(O)=O)OC(=O)[C@@H](C)CC ChemAxon formula C23H36O7 ChemAxon inchi InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 ChemAxon inchikey TUZYXOIXSAXUGO-PZAWKZKUSA-N ChemAxon polar_surface_area 124.29 ChemAxon refractivity 113.6 ChemAxon polarizability 46.56 ChemAxon rotatable_bond_count 11 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7267625a08> DB00175 54687 4720 BE0000574 BE0002366