1.0 2016-05-25 18:10:06 UTC 2026-05-14 17:46:00 UTC Uridine SmallMolecule Uridine belongs to the pyrimidine nucleosides, a class of nucleosides, nucleotides, and analogues within the organic compounds. It has the chemical formula C9H12N2O6 and an average molecular weight of 244.20 g/mol. Biologically, uridine acts as an agonist (PMC12349724) and an antioxidant (PMC13072972). It has a therapeutic effect on inflammation (PMC6348798). The compound interacts with three recorded protein targets: Thymidine phosphorylase (TYMP), the Nucleoside-specific channel-forming protein tsx, and it serves as an inhibitor of the U6 snRNA-associated Sm-like protein LSm6 (LSM6). Industrially, uridine is utilized as a humectant as well as a softener and conditioner. It is found in or released from 16 recorded sources. These include household cleaning and consumer products such as soap detergents, tobacco smoke filters, perfumes within detergents and soaps, and cigar cigarettes. It is also associated with electrical and electronic equipment, specifically X ray tubes, electrodes, antennas, television systems, and conductors or conductive bodies characterised by the conductive materials. Furthermore, uridine is found in food, food processing and cookware, including the preparation of malt, preparation of vinegar, preparation of wine or sparkling wine, fermentation processes for beer, food preservation, and two additional sources. C9H12N2O6 244.2014 244.069536126 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione uridine 58-96-8 OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 DRTQHJPVMGBUCF-XVFCMESISA-N Organic compounds Nucleosides, nucleotides, and analogues Pyrimidine nucleosides Pyrimidine nucleosides Azacyclic compounds Glycosylamines Heteroaromatic compounds Hydrocarbon derivatives Hydropyrimidines Lactams Organic oxides Organonitrogen compounds Organopnictogen compounds Oxacyclic compounds Pentoses Primary alcohols Pyrimidones Secondary alcohols Tetrahydrofurans Ureas Vinylogous amides Alcohol Aromatic heteromonocyclic compound Azacycle Glycosyl compound Heteroaromatic compound Hydrocarbon derivative Hydropyrimidine Lactam Monosaccharide N-glycosyl compound Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Pentose monosaccharide Primary alcohol Pyrimidine Pyrimidine nucleoside Pyrimidone Secondary alcohol Tetrahydrofuran Urea Vinylogous amide Aromatic heteromonocyclic compounds Ribonucleosides uridines Detected and Not Quantified Pyrimidine Metabolism SMP0000046 beta-Ureidopropionase Deficiency SMP0000172 UMP Synthase Deficiency (Orotic Aciduria) SMP0000219 Dihydropyrimidinase Deficiency SMP0000178 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) SMP0000202 Metabolism and Physiological Effects of Uridine SMP0124871 beta-Ureidopropionase Deficiency SMP0125716 UMP Synthase Deficiency (Orotic Aciduria) SMP0125717 Dihydropyrimidinase Deficiency SMP0125719 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) SMP0125720 logp -2.4 logp -1.84 ALOGPS logs -0.26 ALOGPS solubility 1.35e+02 g/l ALOGPS logp -2.4 ChemAxon pka_strongest_acidic 9.7 ChemAxon pka_strongest_basic -3 ChemAxon iupac 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione ChemAxon average_mass 244.2014 ChemAxon mono_mass 244.069536126 ChemAxon smiles OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O ChemAxon formula C9H12N2O6 ChemAxon inchi InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1 ChemAxon inchikey DRTQHJPVMGBUCF-XVFCMESISA-N ChemAxon polar_surface_area 119.33 ChemAxon refractivity 52.57 ChemAxon polarizability 21.81 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 6 ChemAxon donor_count 4 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7278d5ae70> DB02745 6029 BE0004434 BE0002061 BE0002193