1.0 2016-05-25 18:11:01 UTC 2026-05-14 18:59:01 UTC Tryptamine SmallMolecule Tryptamine (C10H12N2) is an organic compound with an average molecular weight of 160.22 g/mol. Tryptamine belongs to the tryptamines and derivatives, a subclass of indoles and derivatives within the organic compounds. Biologically, it serves as a neurotransmitter (PMC8213022). It acts as an inhibitor for five recorded protein targets, including Aralkylamine dehydrogenase light chain (aauA), Aralkylamine dehydrogenase heavy chain (aauB), Amine oxidase [flavin-containing] B (MAOB), and 5-hydroxytryptamine receptor 2A (HTR2A). The compound is found in or released from 36 recorded sources across various sectors. These include Electrical & Electronic Equipment such as cell phones, capacitors, wires and cables, batteries, and printed circuit boards; Household cleaning & consumer products including perfumes within detergents and soaps, cigar cigarettes, non electric simulated smoking devices, other smoking requisites, and pipe accessories; Food, food processing & cookware including food packaging, food contact materials, food preservation, preparation of vinegar, and fermentation processes for beer; Textiles, leather & furnishings such as synthetic textiles, carpets and rugs; Healthcare, pharmaceuticals & veterinary products via medical devices; and Energy, oil & gas through lubricants. Recorded exposure routes include oral, inhalation, and touch. Tryptamine is a biomarker of hypothyroidism (PMC7009407). Blood levels are elevated in cases of obesity (PMC10372128), thyroid cancer (PMC7998837), and hypothyroidism (PMC6915086, PMC7009407). It is further associated with vomiting (PMC9775352), nausea (PMC9775352), hyperthyroidism (increase) (PMC10593800), thyroid cancer (decrease) (PMC10593800), and hypothyroidism (PMC2592280, PMC10593800, PMC12695664, PMC13024578). Conversely, blood levels are decreased in hyperthyroidism (PMC1492602, PMC6915086). PFAS Phytotoxin C10H12N2 160.2157 160.100048394 2-(1H-indol-3-yl)ethan-1-amine tryptamine 61-54-1 NCCC1=CNC2=CC=CC=C12 InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2 APJYDQYYACXCRM-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Indoles and derivatives Tryptamines and derivatives Tryptamines and derivatives 2-arylethylamines 3-alkylindoles Aralkylamines Azacyclic compounds Benzenoids Heteroaromatic compounds Hydrocarbon derivatives Monoalkylamines Organopnictogen compounds Substituted pyrroles 2-arylethylamine 3-alkylindole Amine Aralkylamine Aromatic heteropolycyclic compound Azacycle Benzenoid Heteroaromatic compound Hydrocarbon derivative Indole Organic nitrogen compound Organonitrogen compound Organopnictogen compound Primary aliphatic amine Primary amine Pyrrole Substituted pyrrole Tryptamine Aromatic heteropolycyclic compounds Indole alkaloids aminoalkylindole aralkylamino compound indole alkaloid tryptamines Detected and Not Quantified Tryptophan Metabolism SMP0000063 logp 1.49 logp 1.21 ALOGPS logs -2.08 ALOGPS solubility 1.34e+00 g/l ALOGPS logp 1.49 ChemAxon pka_strongest_acidic 17.17 ChemAxon pka_strongest_basic 9.73 ChemAxon iupac 2-(1H-indol-3-yl)ethan-1-amine ChemAxon average_mass 160.2157 ChemAxon mono_mass 160.100048394 ChemAxon smiles NCCC1=CNC2=CC=CC=C12 ChemAxon formula C10H12N2 ChemAxon inchi InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2 ChemAxon inchikey APJYDQYYACXCRM-UHFFFAOYSA-N ChemAxon polar_surface_area 41.81 ChemAxon refractivity 50.37 ChemAxon polarizability 18.34 ChemAxon rotatable_bond_count 2 ChemAxon acceptor_count 1 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3baf14dc18> DB08653 1150 1118 BE0004362 BE0004363 BE0002196 BE0000451 BE0002198