1.0 2016-05-25 18:19:04 UTC 2026-08-21 19:00:11 UTC Moxifloxacin SmallMolecule Moxifloxacin is an organic compound with the formula C21H24FN3O4 and an average molecular weight of 401.43 g/mol. Moxifloxacin belongs to the quinoline carboxylic acids, a subclass of quinolines and derivatives within the organic compounds. It is categorized under the superclass of organoheterocyclic compounds. The compound is found in or released from nine recorded sources. These include pharmaceuticals and veterinary products, specifically antibiotics, antiinfectives, and quinolone antibacterials, as well as healthcare sources. Additionally, it is associated with food, food processing and cookware, specifically processing meats, and household cleaning and consumer products such as tobacco pipes, non electric simulated smoking devices, and other smoking requisites. It is also linked to electrical and electronic equipment, including video games and television systems. Recorded exposure routes for moxifloxacin include oral, intravenous, ophthalmic, intraocular, and inhalation. In terms of biological activity, moxifloxacin interacts with five recorded protein targets. It acts as an inhibitor or modulator of DNA gyrase subunit A (gyrA), DNA topoisomerase 4 subunit A (parC), DNA topoisomerase 2-alpha (TOP2A), and serum paraoxonase/arylesterase 1 (PON1), along with one other protein. C21H24FN3O4 401.4314 401.175084476 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid moxifloxacin 354812-41-2 [H][C@]12CN(C[C@@]1([H])NCCC2)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1OC)C(O)=O InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 FABPRXSRWADJSP-MEDUHNTESA-N Organic compounds Organoheterocyclic compounds Quinolines and derivatives Quinoline carboxylic acids Quinoline carboxylic acids Alkyl aryl ethers Amino acids Aminoquinolines and derivatives Anisoles Aryl fluorides Azacyclic compounds Carboxylic acids Dialkylamines Dialkylarylamines Fluoroquinolones Haloquinolines Heteroaromatic compounds Hydrocarbon derivatives Hydroquinolines Hydroquinolones Methoxyanilines Monocarboxylic acids and derivatives Organic oxides Organofluorides Organopnictogen compounds Piperidines Pyridinecarboxylic acids Pyrrolidines Pyrrolopyridines Vinylogous amides Alkyl aryl ether Amine Amino acid Amino acid or derivatives Aminoquinoline Anisole Aromatic heteropolycyclic compound Aryl fluoride Aryl halide Azacycle Benzenoid Carboxylic acid Carboxylic acid derivative Dialkylarylamine Dihydroquinoline Dihydroquinolone Ether Fluoroquinolone Haloquinoline Heteroaromatic compound Hydrocarbon derivative Methoxyaniline Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Piperidine Pyridine Pyridine carboxylic acid Pyridine carboxylic acid or derivatives Pyrrolidine Pyrrolopyridine Quinoline-3-carboxylic acid Secondary aliphatic amine Secondary amine Tertiary aliphatic/aromatic amine Tertiary amine Vinylogous amide Aromatic heteropolycyclic compounds aromatic ether cyclopropanes fluoroquinolone antibiotic pyrrolidinopiperidine quinolinemonocarboxylic acid quinolone quinolone antibiotic Detected and Not Quantified Moxifloxacin Drug Metabolism Action Pathway SMP0142680 logp -0.51 logp 0.01 ALOGPS logs -3.38 ALOGPS solubility 1.68e-01 g/l ALOGPS logp -0.5 ChemAxon pka_strongest_acidic 5.69 ChemAxon pka_strongest_basic 9.42 ChemAxon iupac 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ChemAxon average_mass 401.4314 ChemAxon mono_mass 401.175084476 ChemAxon smiles [H][C@]12CN(C[C@@]1([H])NCCC2)C1=C(F)C=C2C(=O)C(=CN(C3CC3)C2=C1OC)C(O)=O ChemAxon formula C21H24FN3O4 ChemAxon inchi InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1 ChemAxon inchikey FABPRXSRWADJSP-MEDUHNTESA-N ChemAxon polar_surface_area 82.11 ChemAxon refractivity 106.22 ChemAxon polarizability 41.24 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 7 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bb3fe5bf0> DB00218 152946 134802 BE0000366 BE0000429 BE0000742 BE0000930 BE0008385 BE0002388