1.0 2016-05-25 18:19:20 UTC 2026-08-18 04:25:05 UTC Anagrelide SmallMolecule Anagrelide is an organic compound with the formula C10H7Cl2N3O and an average molecular weight of 256.09 g/mol. Anagrelide belongs to the benzodiazines, a subclass of diazanaphthalenes within the organic compounds. It is recorded as an inhibitor of the protein target cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (PDE3A). The compound is found in or released from two recorded sources: antennas within electrical and electronic equipment, and antineoplastic agents used in healthcare, pharmaceuticals, and veterinary products. The recorded route of exposure for this substance is oral. C10H7Cl2N3O 256.088 254.996617275 6,7-dichloro-1H,2H,3H,5H-imidazolidino[2,1-b]quinazolin-2-one anagrelide 68475-42-3 ClC1=CC=C2N=C3NC(=O)CN3CC2=C1Cl InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16) OTBXOEAOVRKTNQ-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Diazanaphthalenes Benzodiazines Quinazolines Aryl chlorides Azacyclic compounds Benzenoids Hydrocarbon derivatives Imidazolines Organochlorides Organonitrogen compounds Organooxygen compounds Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds 3-imidazoline Aromatic heteropolycyclic compound Aryl chloride Aryl halide Azacycle Benzenoid Hydrocarbon derivative Organic 1,3-dipolar compound Organic nitrogen compound Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Propargyl-type 1,3-dipolar organic compound Quinazoline Aromatic heteropolycyclic compounds imidazoquinazoline Detected and Not Quantified Anagrelide Drug Metabolism Action Pathway SMP0142722 logp 1.94 logp 1.95 ALOGPS logs -2.96 ALOGPS solubility 2.79e-01 g/l ALOGPS logp 1.94 ChemAxon pka_strongest_acidic 12.55 ChemAxon pka_strongest_basic 3.62 ChemAxon iupac 6,7-dichloro-1H,2H,3H,5H-imidazolidino[2,1-b]quinazolin-2-one ChemAxon average_mass 256.088 ChemAxon mono_mass 254.996617275 ChemAxon smiles ClC1=CC=C2N=C3NC(=O)CN3CC2=C1Cl ChemAxon formula C10H7Cl2N3O ChemAxon inchi InChI=1S/C10H7Cl2N3O/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7/h1-2H,3-4H2,(H,13,14,16) ChemAxon inchikey OTBXOEAOVRKTNQ-UHFFFAOYSA-N ChemAxon polar_surface_area 44.7 ChemAxon refractivity 63.25 ChemAxon polarizability 23.61 ChemAxon rotatable_bond_count 0 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7226c10008> DB00261 2182 2097 BE0000436