1.0 2016-05-25 18:20:05 UTC 2026-08-18 12:03:27 UTC Mexiletine SmallMolecule Mexiletine belongs to the phenol ethers, a class of benzenoids within the organic compounds. It has the chemical formula C11H17NO and an average molecular weight of 179.26 g/mol. The compound functions as a biological drug (PMC7426781). Its recorded protein targets include the Aryl hydrocarbon receptor (AHR) and the Sodium channel protein type 5 subunit alpha (SCN5A), for which it acts as an agonist or inhibitor. Mexiletine is found in or released from ten recorded sources. Within the category of healthcare, pharmaceuticals, and veterinary products, it is used as an antiarrhythmic of class I and III. It is also associated with food preservation in the context of food, food processing, and cookware. Other recorded sources include electrical and electronic equipment, such as antennas, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. Additionally, it is found in household cleaning and consumer products, specifically perfumes within detergents and soaps, tobacco smoke filters, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. The recorded route of exposure for this compound is oral. Human Neurotoxin C11H17NO 179.2588 179.131014171 1-(2,6-dimethylphenoxy)propan-2-amine 1-(2,6-dimethylphenoxy)propan-2-amine 31828-71-4 CC(N)COC1=C(C)C=CC=C1C InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3 VLPIATFUUWWMKC-UHFFFAOYSA-N Organic compounds Benzenoids Phenol ethers Phenol ethers Alkyl aryl ethers Hydrocarbon derivatives Monoalkylamines Organopnictogen compounds Phenoxy compounds m-Xylenes Alkyl aryl ether Amine Aromatic homomonocyclic compound Ether Hydrocarbon derivative M-xylene Monocyclic benzene moiety Organic nitrogen compound Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenol ether Phenoxy compound Primary aliphatic amine Primary amine Xylene Aromatic homomonocyclic compounds aromatic ether primary amino compound Detected and Not Quantified Mexiletine Action Pathway SMP0000329 Mexiletine Action Pathway (New) SMP0126263 Mexiletine Drug Metabolism Action Pathway SMP0142837 logp 2.46 logp 2.17 ALOGPS logs -2.52 ALOGPS solubility 5.38e-01 g/l ALOGPS logp 2.46 ChemAxon pka_strongest_basic 9.52 ChemAxon iupac 1-(2,6-dimethylphenoxy)propan-2-amine ChemAxon average_mass 179.2588 ChemAxon mono_mass 179.131014171 ChemAxon smiles CC(N)COC1=C(C)C=CC=C1C ChemAxon formula C11H17NO ChemAxon inchi InChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3 ChemAxon inchikey VLPIATFUUWWMKC-UHFFFAOYSA-N ChemAxon polar_surface_area 35.25 ChemAxon refractivity 54.97 ChemAxon polarizability 21.17 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 2 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7223330b48> DB00379 4178 4034 BE0000197 BE0003721