1.0 2016-05-25 18:20:49 UTC 2026-08-19 10:09:11 UTC Tolmetin SmallMolecule Tolmetin is an organic compound with the chemical formula C15H15NO3 and an average molecular weight of 257.28 g/mol. Tolmetin belongs to the carbonyl compounds, a subclass of organooxygen compounds within the organic compounds. This compound is associated with 15 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is found in antiinflammatory and antirheumatic products as well as topical products for joint and muscular pain. In the category of food, food processing, and cookware, it is used in food preservation. It is also released from household cleaning and consumer products, including perfumes within detergents and soaps, pipe accessories, tobacco smoke filters, other smoking requisites, and non electric simulated smoking devices. Additionally, it is found in electrical and electronic equipment, such as antennas, conductors or conductive bodies characterised by the conductive materials, electrically stimulated smoking devices, electrodes, hybrid capacitors, and two other sources. The recorded route of exposure for tolmetin is oral. Regarding its biological activity, the compound acts on two recorded protein targets, serving as an inhibitor of Prostaglandin G/H synthase 1 (PTGS1) and Prostaglandin G/H synthase 2 (PTGS2). Human Neurotoxin C15H15NO3 257.2845 257.105193351 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid tolmetin 26171-23-3 CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1 InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) UPSPUYADGBWSHF-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aryl-phenylketones Azacyclic compounds Benzoyl derivatives Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives N-methylpyrroles Organic oxides Organonitrogen compounds Organopnictogen compounds Toluenes Aromatic heteromonocyclic compound Aryl-phenylketone Azacycle Benzenoid Benzoyl Carboxylic acid Carboxylic acid derivative Heteroaromatic compound Hydrocarbon derivative Monocarboxylic acid or derivatives Monocyclic benzene moiety N-methylpyrrole Organic nitrogen compound Organic oxide Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Pyrrole Substituted pyrrole Toluene Aromatic heteromonocyclic compounds aromatic ketone monocarboxylic acid pyrroles Detected and Not Quantified Tolmetin Action Pathway SMP0000704 Tolmetin Action Pathway (New) SMP0124606 Tolmetin Drug Metabolism Action Pathway SMP0142954 logp 2.73 logp 2.81 ALOGPS logs -3.29 ALOGPS solubility 1.31e-01 g/l ALOGPS logp 2.73 ChemAxon pka_strongest_acidic 3.96 ChemAxon pka_strongest_basic -7.8 ChemAxon iupac 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid ChemAxon average_mass 257.2845 ChemAxon mono_mass 257.105193351 ChemAxon smiles CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1 ChemAxon formula C15H15NO3 ChemAxon inchi InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) ChemAxon inchikey UPSPUYADGBWSHF-UHFFFAOYSA-N ChemAxon polar_surface_area 59.3 ChemAxon refractivity 72.39 ChemAxon polarizability 27.67 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 3 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72832ec3c0> DB00500 5509 5308 BE0000017 BE0000262