1.0 2016-05-25 18:22:12 UTC 2026-08-21 22:21:39 UTC Moricizine SmallMolecule Moricizine is an organic compound with the formula C22H25N3O4S and an average molecular weight of 427.52 g/mol. Moricizine belongs to the phenothiazines, a subclass of benzothiazines within the organic compounds. It functions as an inhibitor of the sodium channel protein type 5 subunit alpha (SCN5A). The compound is found in or released from four recorded sources, including healthcare, pharmaceuticals and veterinary products as class i and iii antiarrhythmics, household cleaning and consumer products such as cigar cigarettes and other smoking requisites, and electrically stimulated smoking devices from electrical and electronic equipment. The recorded exposure route for moricizine is oral. C22H25N3O4S 427.517 427.156576993 ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate moricizine 31883-05-3 CCOC(=O)NC1=CC2=C(SC3=CC=CC=C3N2C(=O)CCN2CCOCC2)C=C1 InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27) FUBVWMNBEHXPSU-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzothiazines Phenothiazines Phenothiazines 1,4-thiazines Azacyclic compounds Benzenoids Beta amino acids and derivatives Carbonyl compounds Carboximidic acids and derivatives Dialkyl ethers Diarylthioethers Hydrocarbon derivatives Morpholines Organic oxides Organopnictogen compounds Oxacyclic compounds Propargyl-type 1,3-dipolar organic compounds Tertiary carboxylic acid amides Trialkylamines Amine Amino acid or derivatives Aromatic heteropolycyclic compound Aryl thioether Azacycle Benzenoid Beta amino acid or derivatives Carbonyl group Carboxamide group Carboximidic acid derivative Carboxylic acid derivative Dialkyl ether Diarylthioether Ether Hydrocarbon derivative Morpholine Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Oxacycle Oxazinane Para-thiazine Phenothiazine Propargyl-type 1,3-dipolar organic compound Tertiary aliphatic amine Tertiary amine Tertiary carboxylic acid amide Thioether Aromatic heteropolycyclic compounds carbamate ester morpholines phenothiazines Detected and Not Quantified Moricizine Action Pathway SMP0126950 Moricizine Drug Metabolism SMP0130929 Moricizine Drug Metabolism Action Pathway SMP0143124 logp 3.07 logp 3.04 ALOGPS logs -4.10 ALOGPS solubility 3.39e-02 g/l ALOGPS logp 3.07 ChemAxon pka_strongest_acidic 12.9 ChemAxon pka_strongest_basic 6.73 ChemAxon iupac ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate ChemAxon average_mass 427.517 ChemAxon mono_mass 427.156576993 ChemAxon smiles CCOC(=O)NC1=CC2=C(SC3=CC=CC=C3N2C(=O)CCN2CCOCC2)C=C1 ChemAxon formula C22H25N3O4S ChemAxon inchi InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27) ChemAxon inchikey FUBVWMNBEHXPSU-UHFFFAOYSA-N ChemAxon polar_surface_area 71.11 ChemAxon refractivity 118.88 ChemAxon polarizability 45.27 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 5 ChemAxon donor_count 1 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f726f323fc8> DB00680 34633 31872 BE0000197