1.0 2016-05-25 18:22:18 UTC 2026-05-14 16:46:04 UTC Pentosan Polysulfate SmallMolecule Pentosan Polysulfate is an organic compound with the formula C10H18O21S4. Pentosan Polysulfate belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. With an average molecular weight of 602.50 g/mol, Pentosan Polysulfate is a heavy molecule. This compound is found in or released from two recorded sources: healthcare, pharmaceuticals, and veterinary products, specifically as urologicals and vasoprotectives. The recorded route of exposure for this substance is oral. In terms of biological activity, Pentosan Polysulfate interacts with three recorded protein targets, acting as an antagonist or inhibitor of fibroblast growth factor 1 (FGF1), fibroblast growth factor 2 (FGF2), and fibroblast growth factor 4 (FGF4). Human Neurotoxin C10H18O21S4 602.497 601.922340398 [(2S,3R,4S,5R)-5-hydroxy-2-{[(3R,4S,5R,6R)-6-hydroxy-4,5-bis(sulfooxy)oxan-3-yl]oxy}-4-(sulfooxy)oxan-3-yl]oxidanesulfonic acid pentosan polysulfate 37300-21-3 O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O InChI=1S/C10H18O21S4/c11-3-1-26-10(8(31-35(22,23)24)5(3)28-32(13,14)15)27-4-2-25-9(12)7(30-34(19,20)21)6(4)29-33(16,17)18/h3-12H,1-2H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)/t3-,4-,5+,6+,7-,8-,9-,10+/m1/s1 FCCNSUIJIOOXEZ-SJYYZXOBSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates O-glycosyl compounds Acetals Alkyl sulfates Disaccharides Hemiacetals Hydrocarbon derivatives Organic oxides Oxacyclic compounds Oxanes Secondary alcohols Sulfuric acid monoesters Acetal Alcohol Aliphatic heteromonocyclic compound Alkyl sulfate Disaccharide Hemiacetal Hydrocarbon derivative O-glycosyl compound Organic oxide Organic sulfuric acid or derivatives Organoheterocyclic compound Oxacycle Oxane Secondary alcohol Sulfate-ester Sulfuric acid ester Sulfuric acid monoester Aliphatic heteromonocyclic compounds Detected and Not Quantified Pentosan polysulfate Drug Metabolism SMP0130719 Pentosan polysulfate Drug Metabolism Action Pathway SMP0143130 logp -11 logp -2.49 ALOGPS logs -2.24 ALOGPS solubility 3.49e+00 g/l ALOGPS logp -11 ChemAxon pka_strongest_acidic -2.9 ChemAxon pka_strongest_basic -3.6 ChemAxon iupac [(2S,3R,4S,5R)-5-hydroxy-2-{[(3R,4S,5R,6R)-6-hydroxy-4,5-bis(sulfooxy)oxan-3-yl]oxy}-4-(sulfooxy)oxan-3-yl]oxidanesulfonic acid ChemAxon average_mass 602.497 ChemAxon mono_mass 601.922340398 ChemAxon smiles O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O ChemAxon formula C10H18O21S4 ChemAxon inchi InChI=1S/C10H18O21S4/c11-3-1-26-10(8(31-35(22,23)24)5(3)28-32(13,14)15)27-4-2-25-9(12)7(30-34(19,20)21)6(4)29-33(16,17)18/h3-12H,1-2H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)/t3-,4-,5+,6+,7-,8-,9-,10+/m1/s1 ChemAxon inchikey FCCNSUIJIOOXEZ-SJYYZXOBSA-N ChemAxon polar_surface_area 322.55 ChemAxon refractivity 96.38 ChemAxon polarizability 46.17 ChemAxon rotatable_bond_count 10 ChemAxon acceptor_count 17 ChemAxon donor_count 6 ChemAxon physiological_charge -4 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f722667aaa8> DB00686 37720 BE0000689 BE0000326 BE0001015