1.0 2016-05-25 18:22:42 UTC 2026-08-22 05:38:20 UTC Deferoxamine SmallMolecule Deferoxamine (C25H48N6O8) is a compound that functions biologically as a siderophore, an iron chelator (PMC4507282), and a chelator (PMC10855613). Deferoxamine belongs to the carboxylic acid derivatives, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 560.68 g/mol, Deferoxamine is a heavy molecule. It acts as a downregulator of the protein target Amyloid-beta precursor protein (APP). The compound is found in or released from 18 recorded sources, including food preservation, unclassified therapeutic products, stairs and ramps, and household cleaning and consumer products such as soap detergents, bleaching agents, cigar cigarettes, non electric simulated smoking devices, and other smoking requisites. It is also associated with electrical and electronic equipment, including electric switches, electrically stimulated smoking devices, electric hearing aids, and conductors or conductive bodies characterised by the conductive materials, cores yokes or armatures. Recorded exposure routes include subcutaneous, intravenous, intraperitoneal, and intramuscular administration, while literature supports inhalation as an exposure route (PMC3359900). In terms of health effects, Deferoxamine is used as a treatment for ischemic stroke (PMC8913707) and hemochromatosis (PMC11308372). It has a therapeutic effect on pulmonary fibrosis (PMC13006651) but is associated with anemia (PMC5384363). Human Neurotoxin C25H48N6O8 560.684 560.353362542 N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl]butanediamide N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl]succinamide 70-51-9 CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN InChI=1S/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34) UBQYURCVBFRUQT-UHFFFAOYSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Acetohydroxamic acids Acetamides Amino acids and derivatives Carbonyl compounds Carboximidic acids Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds Propargyl-type 1,3-dipolar organic compounds Acetamide Acetohydroxamic acid Aliphatic acyclic compound Amine Amino acid or derivatives Carbonyl group Carboximidic acid Carboximidic acid derivative Hydrocarbon derivative Organic 1,3-dipolar compound Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Primary aliphatic amine Primary amine Propargyl-type 1,3-dipolar organic compound Aliphatic acyclic compounds a hydroxamate siderophore acyclic desferrioxamine Detected and Not Quantified Deferoxamine Drug Metabolism SMP0130854 Deferoxamine Drug Metabolism Action Pathway SMP0143189 logp -3.4 logp 0.93 ALOGPS logs -3.75 ALOGPS solubility 9.90e-02 g/l ALOGPS logp -3.4 ChemAxon pka_strongest_acidic 7.92 ChemAxon pka_strongest_basic 10.23 ChemAxon iupac N-(5-aminopentyl)-N-hydroxy-N'-[5-(N-hydroxy-3-{[5-(N-hydroxyacetamido)pentyl]carbamoyl}propanamido)pentyl]butanediamide ChemAxon average_mass 560.684 ChemAxon mono_mass 560.353362542 ChemAxon smiles CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN ChemAxon formula C25H48N6O8 ChemAxon inchi InChI=1S/C25H48N6O8/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34) ChemAxon inchikey UBQYURCVBFRUQT-UHFFFAOYSA-N ChemAxon polar_surface_area 205.84 ChemAxon refractivity 144.95 ChemAxon polarizability 62.41 ChemAxon rotatable_bond_count 23 ChemAxon acceptor_count 9 ChemAxon donor_count 6 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf3799880> DB00746 2973 2867 BE0003392