1.0 2016-05-25 18:22:44 UTC 2026-08-19 02:02:46 UTC Prilocaine SmallMolecule Prilocaine is an organic compound with the chemical formula C13H20N2O and an average molecular weight of 220.31 g/mol. Prilocaine belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. It acts as an inhibitor of the sodium channel protein type 5 subunit alpha (SCN5A). The substance is identified in eleven recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used as an anesthetic. It is also associated with food preservation in food, food processing, and cookware. Other recorded sources include household cleaning and consumer products—specifically perfumes within detergents and soaps, tobacco smoke filters, cigar cigarettes, other smoking requisites, and non-electric simulated smoking devices—as well as electrical and electronic equipment, including video games, electric hearing aids, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. Exposure to prilocaine occurs through multiple recorded routes. These include intravenous, intramuscular, subcutaneous, and intra-articular infiltration, as well as oral, dental, periodontal, submucosal, topical, and cutaneous administration. Human Neurotoxin C13H20N2O 220.3107 220.157563272 N-(2-methylphenyl)-2-(propylamino)propanamide prilocaine 721-50-6 CCCNC(C)C(=O)NC1=CC=CC=C1C InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16) MVFGUOIZUNYYSO-UHFFFAOYSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Alpha amino acid amides Alanine and derivatives Anilides Carbonyl compounds Dialkylamines Hydrocarbon derivatives N-arylamides Organic oxides Organopnictogen compounds Secondary carboxylic acid amides Toluenes Alanine or derivatives Alpha-amino acid amide Amine Anilide Aromatic homomonocyclic compound Benzenoid Carbonyl group Carboxamide group Hydrocarbon derivative Monocyclic benzene moiety N-arylamide Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Secondary aliphatic amine Secondary amine Secondary carboxylic acid amide Toluene Aromatic homomonocyclic compounds amino acid amide monocarboxylic acid amide Detected and Not Quantified Prilocaine Action Pathway SMP0000401 Prilocaine Drug Metabolism Action Pathway SMP0143193 logp 2.68 logp 1.87 ALOGPS logs -2.83 ALOGPS solubility 3.26e-01 g/l ALOGPS logp 2.68 ChemAxon pka_strongest_acidic 13.51 ChemAxon pka_strongest_basic 8.82 ChemAxon iupac N-(2-methylphenyl)-2-(propylamino)propanamide ChemAxon average_mass 220.3107 ChemAxon mono_mass 220.157563272 ChemAxon smiles CCCNC(C)C(=O)NC1=CC=CC=C1C ChemAxon formula C13H20N2O ChemAxon inchi InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16) ChemAxon inchikey MVFGUOIZUNYYSO-UHFFFAOYSA-N ChemAxon polar_surface_area 41.13 ChemAxon refractivity 67.86 ChemAxon polarizability 25.98 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f86bb258660> DB00750 4906 4737 BE0000197