1.0 2016-05-25 18:22:59 UTC 2026-08-19 16:48:00 UTC Tripelennamine SmallMolecule Tripelennamine is an organic compound with the formula C16H21N3 and an average molecular weight of 255.36 g/mol. Tripelennamine belongs to the benzylamines, a subclass of benzene and substituted derivatives within the organic compounds. This compound is found in or released from seven recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically as antihistamines and antipruritics. It is also associated with electrical and electronic equipment, such as antennas and electrically stimulated smoking devices, as well as household cleaning and consumer products, including tobacco smoke filters and perfumes within detergents and soaps. Additionally, it is found in food contact materials used in food, food processing, and cookware. Recorded exposure routes for tripelennamine include oral, inhalation, topical, vaginal, and touch. Regarding its biological activity, one protein target is recorded: the compound acts as an antagonist of the Histamine H1 receptor (HRH1). C16H21N3 255.358 255.173547687 N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine tripelennamine 91-81-6 CN(C)CCN(CC1=CC=CC=C1)C1=CC=CC=N1 InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3 UFLGIAIHIAPJJC-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzylamines 2-benzylaminopyridines Aminopyridines and derivatives Azacyclic compounds Dialkylarylamines Heteroaromatic compounds Hydrocarbon derivatives Imidolactams Organopnictogen compounds Trialkylamines 2-benzylaminopyridine Amine Aminopyridine Aromatic heteromonocyclic compound Azacycle Dialkylarylamine Heteroaromatic compound Hydrocarbon derivative Imidolactam Organic nitrogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Pyridine Tertiary aliphatic amine Tertiary amine Aromatic heteromonocyclic compounds aromatic amine Detected and Not Quantified Tripelennamine H1-Antihistamine Action SMP0057587 Tripelennamine Drug Metabolism Action Pathway SMP0143231 Tripelennamine H1 Antihistamine Smooth Muscle Relaxation Action Pathway SMP0174897 Tripelennamine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174989 Tripelennamine H1-Antihistamine Immune Response Action Pathway SMP0175081 logp 3.2 logp 3.05 ALOGPS logs -1.95 ALOGPS solubility 2.84e+00 g/l ALOGPS logp 3.2 ChemAxon pka_strongest_basic 8.76 ChemAxon iupac N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine ChemAxon average_mass 255.358 ChemAxon mono_mass 255.173547687 ChemAxon smiles CN(C)CCN(CC1=CC=CC=C1)C1=CC=CC=N1 ChemAxon formula C16H21N3 ChemAxon inchi InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3 ChemAxon inchikey UFLGIAIHIAPJJC-UHFFFAOYSA-N ChemAxon polar_surface_area 19.37 ChemAxon refractivity 81.27 ChemAxon polarizability 29.86 ChemAxon rotatable_bond_count 6 ChemAxon acceptor_count 3 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f3bf30de248> DB00792 5587 5385 BE0000442