1.0 2016-05-25 18:23:37 UTC 2026-08-18 01:30:57 UTC Phenformin SmallMolecule Phenformin is an organic nitrogen compound with the chemical formula C10H15N5 and an average molecular weight of 205.26 g/mol. Phenformin belongs to the guanidines, a subclass of organonitrogen compounds within the organic compounds. This compound is associated with 16 recorded sources. Within the category of electrical and electronic equipment, it is found in antennas, amplifiers, colour television systems, auxiliary devices, and conductors or conductive bodies characterised by the conductive materials, among eight other sources. In the realm of household cleaning and consumer products, it is released from pipe accessories and bleaching agents. Additionally, it is found in food preservation within the category of food, food processing, and cookware. At the molecular level, phenformin interacts with four recorded protein targets. It acts as an activator or inhibitor of the 5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1). It also targets the 5'-AMP-activated protein kinase subunit beta-1 (PRKAB1), the 5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1), and the ATP-sensitive inward rectifier potassium channel 8 (KCNJ8). Human Neurotoxin C10H15N5 205.2596 205.132745505 1-carbamimidamido-N-(2-phenylethyl)methanimidamide phenethylbiguanide 114-86-3 NC(=N)NC(=N)NCCC1=CC=CC=C1 InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15) ICFJFFQQTFMIBG-UHFFFAOYSA-N Organic compounds Organic nitrogen compounds Organonitrogen compounds Guanidines Biguanides Benzene and substituted derivatives Carboximidamides Hydrocarbon derivatives Imines Organopnictogen compounds Aromatic homomonocyclic compound Benzenoid Biguanide Carboximidamide Hydrocarbon derivative Imine Monocyclic benzene moiety Organopnictogen compound Aromatic homomonocyclic compounds biguanides Detected and Not Quantified Phenformin Drug Metabolism SMP0130685 Phenformin Drug Metabolism Action Pathway SMP0143347 logp 0.83 logp -0.72 ALOGPS logs -2.95 ALOGPS solubility 2.32e-01 g/l ALOGPS logp 0.83 ChemAxon pka_strongest_basic 11.97 ChemAxon iupac 1-carbamimidamido-N-(2-phenylethyl)methanimidamide ChemAxon average_mass 205.2596 ChemAxon mono_mass 205.132745505 ChemAxon smiles NC(=N)NC(=N)NCCC1=CC=CC=C1 ChemAxon formula C10H15N5 ChemAxon inchi InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15) ChemAxon inchikey ICFJFFQQTFMIBG-UHFFFAOYSA-N ChemAxon polar_surface_area 97.78 ChemAxon refractivity 80.72 ChemAxon polarizability 22.14 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 5 ChemAxon donor_count 5 ChemAxon physiological_charge 2 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f721bee8c18> DB00914 8249 7953 BE0000677 BE0002441 BE0000254 BE0004907