1.0 2016-05-25 18:23:47 UTC 2026-08-19 04:20:07 UTC Meclofenamic acid SmallMolecule Meclofenamic acid is an organic compound with the formula C14H11Cl2NO2 and an average molecular weight of 296.15 g/mol. Meclofenamic acid belongs to the benzoic acids and derivatives, a subclass of benzene and substituted derivatives within the organic compounds. This compound is found in or released from 12 recorded sources, including healthcare, pharmaceuticals & veterinary products such as topical products for joint and muscular pain and antiinflammatory and antirheumatic products. Other sources include food preservation within food, food processing & cookware; drinking water; household cleaning & consumer products including pipe accessories, perfumes within detergents and soaps, non electric simulated smoking devices, bleaching agents, and other smoking requisites; and electrical & electronic equipment such as antennas, electrically stimulated smoking devices, and conductors or conductive bodies characterised by the conductive materials. The recorded exposure route for this substance is oral. Meclofenamic acid acts on five recorded protein targets, serving as an inhibitor or other of prostaglandin G/H synthase 1 (PTGS1), prostaglandin G/H synthase 2 (PTGS2), polyunsaturated fatty acid 5-lipoxygenase (ALOX5), and potassium voltage-gated channel subfamily KQT member 2 (KCNQ2), along with one other protein. Regarding health effects, it has a therapeutic effect on neuropathic pain (PMC7609673). C14H11Cl2NO2 296.149 295.016684015 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid meclofenamic acid 644-62-2 CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1 InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) SBDNJUWAMKYJOX-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Benzoic acids and derivatives Aminobenzoic acids Amino acids Aminotoluenes Aniline and substituted anilines Aryl chlorides Benzoic acids Benzoyl derivatives Carboxylic acids Dichlorobenzenes Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organochlorides Organooxygen compounds Organopnictogen compounds Secondary amines Vinylogous amides 1,3-dichlorobenzene Amine Amino acid Amino acid or derivatives Aminobenzoic acid Aminotoluene Aniline or substituted anilines Aromatic homomonocyclic compound Aryl chloride Aryl halide Benzoic acid Benzoyl Carboxylic acid Carboxylic acid derivative Chlorobenzene Halobenzene Hydrocarbon derivative Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organochloride Organohalogen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Secondary amine Toluene Vinylogous amide Aromatic homomonocyclic compounds aminobenzoic acid organochlorine compound secondary amino compound Detected and Not Quantified Meclofenamic acid Action Pathway SMP0126104 Meclofenamic acid Drug Metabolism Action Pathway SMP0143371 logp 6.09 logp 5.11 ALOGPS logs -4.91 ALOGPS solubility 3.66e-03 g/l ALOGPS logp 6.09 ChemAxon pka_strongest_acidic 3.79 ChemAxon pka_strongest_basic -3.6 ChemAxon iupac 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid ChemAxon average_mass 296.149 ChemAxon mono_mass 295.016684015 ChemAxon smiles CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1 ChemAxon formula C14H11Cl2NO2 ChemAxon inchi InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19) ChemAxon inchikey SBDNJUWAMKYJOX-UHFFFAOYSA-N ChemAxon polar_surface_area 49.33 ChemAxon refractivity 76.45 ChemAxon polarizability 28.44 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727f158710> DB00939 4037 3897 BE0000017 BE0000262 BE0000248 BE0000897 BE0002398