1.0 2016-05-25 18:23:53 UTC 2026-05-14 16:54:02 UTC Netilmicin SmallMolecule Netilmicin is an organic compound with the chemical formula C21H41N5O7 and an average molecular weight of 475.58 g/mol. Netilmicin belongs to the carbohydrates and carbohydrate conjugates, a subclass of organooxygen compounds within the organic compounds. This compound is identified as an inhibitor of the small ribosomal subunit protein uS12 (rpsL). It is found in or released from five recorded sources, including indoor air, antennas within electrical and electronic equipment, and various healthcare, pharmaceuticals, and veterinary products such as antibiotics, antiinfectives, and aminoglycoside antibacterials. Recorded exposure routes for the substance include oral, intravenous, intramuscular, ophthalmic, and inhalation pathways. Human Neurotoxin (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4-amino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-6-(ethylamino)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol C21H41N5O7 475.5795 475.300598691 (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4-amino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-6-(ethylamino)-2-hydroxycyclohexyl]oxy}-3-methyl-4-(methylamino)oxane-3,5-diol netilmicin sulfate 56391-56-1 CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@H](O)[C@@H](NC)[C@@]1(C)O InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)15(28)17(13)33-20-21(2,29)18(25-3)14(27)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15+,16-,17+,18-,19-,20-,21-/m1/s1 ZBGPYVZLYBDXKO-HILBYHGXSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Carbohydrates and carbohydrate conjugates Aminocyclitol glycosides 1,2-aminoalcohols Acetals Aminocyclitols and derivatives Cyclohexanols Cyclohexylamines Dialkylamines Hydrocarbon derivatives Monoalkylamines Monosaccharides O-glycosyl compounds Organopnictogen compounds Oxacyclic compounds Oxanes Tertiary alcohols 1,2-aminoalcohol Acetal Alcohol Aliphatic heteromonocyclic compound Amine Amino cyclitol glycoside Aminocyclitol or derivatives Cyclic alcohol Cyclitol or derivatives Cyclohexanol Cyclohexylamine Glycosyl compound Hydrocarbon derivative Monosaccharide O-glycosyl compound Organic nitrogen compound Organoheterocyclic compound Organonitrogen compound Organopnictogen compound Oxacycle Oxane Primary aliphatic amine Primary amine Secondary alcohol Secondary aliphatic amine Secondary amine Tertiary alcohol Aliphatic heteromonocyclic compounds amino cyclitol glycoside aminoglycoside antibiotic beta-L-arabinoside monosaccharide derivative Detected and Not Quantified Netilmicin Action Pathway SMP0000257 Netilmicin Action Pathway SMP0126750 Netilmicin Drug Metabolism Action Pathway SMP0143385 Netilmicin Predicted Metabolism Pathway SMP0174668 logp -3.5 logp -1.41 ALOGPS logs -1.75 ALOGPS solubility 8.43e+00 g/l ALOGPS logp -3.5 ChemAxon pka_strongest_acidic 12.49 ChemAxon pka_strongest_basic 9.97 ChemAxon iupac (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4-amino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-6-(ethylamino)-2-hydroxycyclohexyl]oxy}-3-methyl-4-(methylamino)oxane-3,5-diol ChemAxon average_mass 475.5795 ChemAxon mono_mass 475.300598691 ChemAxon smiles CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@H](O)[C@@H](NC)[C@@]1(C)O ChemAxon formula C21H41N5O7 ChemAxon inchi InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)15(28)17(13)33-20-21(2,29)18(25-3)14(27)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15+,16-,17+,18-,19-,20-,21-/m1/s1 ChemAxon inchikey ZBGPYVZLYBDXKO-HILBYHGXSA-N ChemAxon polar_surface_area 199.73 ChemAxon refractivity 119.84 ChemAxon polarizability 50.89 ChemAxon rotatable_bond_count 8 ChemAxon acceptor_count 12 ChemAxon donor_count 8 ChemAxon physiological_charge 5 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f72441906f0> DB00955 441306 20152952 BE0000279