1.0 2016-05-25 18:24:11 UTC 2026-08-19 07:19:17 UTC Rivastigmine SmallMolecule Rivastigmine is an organic compound with the formula C14H22N2O2 and an average molecular weight of 250.34 g/mol. Rivastigmine belongs to the phenoxy compounds, a subclass of benzene and substituted derivatives within the organic compounds. It is categorized within the superclass of benzenoids. This compound acts as an inhibitor of two protein targets: cholinesterase (BCHE) and acetylcholinesterase (ACHE). In terms of health effects, rivastigmine is used as a treatment for Alzheimer's disease (PMC4179059). The compound is found in or released from 11 recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is utilized as anti-dementia drugs. Other recorded sources include household cleaning and consumer products, such as soap dispensers, other smoking requisites, and non electric simulated smoking devices. It is also associated with electrical and electronic equipment, including television systems, video games, antennas, amplifiers, and radio transmission systems. Additionally, it is linked to food, food processing, and cookware, specifically the preparation of wine or sparkling wine and the preparation of vinegar. Recorded exposure routes for rivastigmine include transdermal, topical, and oral administration. Human Neurotoxin C14H22N2O2 250.3367 250.168127958 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate exelon 123441-03-2 CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 XSVMFMHYUFZWBK-NSHDSACASA-N Organic compounds Benzenoids Benzene and substituted derivatives Phenoxy compounds Phenoxy compounds Aralkylamines Carbamate esters Carbonyl compounds Hydrocarbon derivatives Organic carbonic acids and derivatives Organic oxides Organopnictogen compounds Trialkylamines Amine Aralkylamine Aromatic homomonocyclic compound Carbamic acid ester Carbonic acid derivative Carbonyl group Hydrocarbon derivative Organic nitrogen compound Organic oxide Organic oxygen compound Organonitrogen compound Organooxygen compound Organopnictogen compound Phenoxy compound Tertiary aliphatic amine Tertiary amine Aromatic homomonocyclic compounds carbamate ester tertiary amino compound Detected and Not Quantified Rivastigmine Action Pathway (new) SMP0126688 Rivastigmine Drug Metabolism Action Pathway SMP0143419 Rivastigmine Predicted Metabolism Pathway SMP0174555 logp 2.41 logp 2.45 ALOGPS logs -2.09 ALOGPS solubility 2.04e+00 g/l ALOGPS logp 2.41 ChemAxon pka_strongest_basic 8.89 ChemAxon iupac 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate ChemAxon average_mass 250.3367 ChemAxon mono_mass 250.168127958 ChemAxon smiles CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C ChemAxon formula C14H22N2O2 ChemAxon inchi InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1 ChemAxon inchikey XSVMFMHYUFZWBK-NSHDSACASA-N ChemAxon polar_surface_area 32.78 ChemAxon refractivity 73.37 ChemAxon polarizability 28.53 ChemAxon rotatable_bond_count 5 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225d90aa0> DB00989 77991 70377 BE0000426 BE0002180