1.0 2016-05-25 18:26:14 UTC 2026-08-20 00:48:44 UTC Trimeprazine SmallMolecule Trimeprazine is an organic compound with the chemical formula C18H22N2S and an average molecular weight of 298.45 g/mol. Trimeprazine belongs to the phenothiazines, a subclass of benzothiazines within the organic compounds. In terms of biological activity, it is recorded as an antagonist of the Histamine H1 receptor (HRH1). The substance is identified in nine recorded sources. Within healthcare, pharmaceuticals, and veterinary products, it is used as an antihistamine. It is also found in food preservation within the food, food processing, and cookware category. Additionally, it is released from household cleaning and consumer products, including soap detergents, perfumes within detergents and soaps, and non electric simulated smoking devices. It is further associated with electrical and electronic equipment, specifically relays, electric switches, fixed capacitors and their manufacture, and electrically stimulated smoking devices. The recorded exposure route for this compound is oral. Human Neurotoxin alimemazine C18H22N2S 298.446 298.150369404 dimethyl[2-methyl-3-(10H-phenothiazin-10-yl)propyl]amine trimeprazine 84-96-8 CC(CN(C)C)CN1C2=CC=CC=C2SC2=CC=CC=C12 InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 ZZHLYYDVIOPZBE-UHFFFAOYSA-N Organic compounds Organoheterocyclic compounds Benzothiazines Phenothiazines Phenothiazines 1,4-thiazines Alkyldiarylamines Azacyclic compounds Benzenoids Diarylthioethers Hydrocarbon derivatives Organopnictogen compounds Trialkylamines Alkyldiarylamine Amine Aromatic heteropolycyclic compound Aryl thioether Azacycle Benzenoid Diarylthioether Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Para-thiazine Phenothiazine Tertiary aliphatic amine Tertiary aliphatic/aromatic amine Tertiary amine Thioether Aromatic heteropolycyclic compounds phenothiazines Detected and Not Quantified Alimemazine H1-Antihistamine Action SMP0059689 Alimemazine Drug Metabolism Action Pathway SMP0143664 Alimemazine H1 Antihistamine Smooth Muscle Relaxation Action Pathway SMP0174905 Alimemazine H1-Antihistamine Blood Vessel Constriction Action Pathway SMP0174997 Alimemazine H1-Antihistamine Immune Response Action Pathway SMP0175089 logp 4.41 logp 4.82 ALOGPS logs -4.55 ALOGPS solubility 8.35e-03 g/l ALOGPS logp 4.41 ChemAxon pka_strongest_basic 9.42 ChemAxon iupac dimethyl[2-methyl-3-(10H-phenothiazin-10-yl)propyl]amine ChemAxon average_mass 298.446 ChemAxon mono_mass 298.150369404 ChemAxon smiles CC(CN(C)C)CN1C2=CC=CC=C2SC2=CC=CC=C12 ChemAxon formula C18H22N2S ChemAxon inchi InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3 ChemAxon inchikey ZZHLYYDVIOPZBE-UHFFFAOYSA-N ChemAxon polar_surface_area 6.48 ChemAxon refractivity 93.37 ChemAxon polarizability 34.83 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7223b32f80> DB01246 5574 5373 BE0000442