1.0 2016-05-25 18:26:47 UTC 2026-08-22 05:08:39 UTC Cefoperazone SmallMolecule Cefoperazone (C25H27N9O8S2) is a chemical compound used as an antibiotic and a beta-lactam antibacterial. Cefoperazone belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. With an average molecular weight of 645.67 g/mol, Cefoperazone is a heavy molecule. The compound is found in or released from 11 recorded sources. These include healthcare, pharmaceuticals and veterinary products, as well as household cleaning and consumer products such as cigar cigarettes and other smoking requisites. It is also associated with electrical and electronic equipment, including television systems, video games, electric switches, electrically stimulated smoking devices, and emergency protective devices. Additionally, it is found in drinking water and water supply, and in food, food processing and cookware, specifically processing meats. Recorded exposure routes for the substance include intravenous, oral, and inhalation. In terms of biological activity, Cefoperazone interacts with eight recorded protein targets. It acts as an inhibitor of penicillin-binding protein 1A (mrcA), penicillin-binding protein 1B (mrcB), peptidoglycan D,D-transpeptidase FtsI (ftsI), and peptidoglycan D,D-transpeptidase MrdA (mrdA), along with four other proteins. C25H27N9O8S2 645.667 645.142400265 (6R,7R)-7-{2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido}-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefoperazonum 62893-19-0 [H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)C(NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15?,16-,22-/m1/s1 GCFBRXLSHGKWDP-WTKTZPJXSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Peptides 1,3-thiazines 1-hydroxy-2-unsubstituted benzenoids Alkylarylthioethers Alpha amino acid amides Azacyclic compounds Azetidines Carbonyl compounds Carboxylic acids Cephalosporins Dialkylthioethers Dicarboximides Dioxopiperazines Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives N-acyl ureas N-acyl-alpha amino acids and derivatives N-alkylpiperazines N-carbamoyl-alpha amino acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Phenylacetamides Piperazine carboxamides Secondary carboxylic acid amides Sulfenyl compounds Tertiary carboxylic acid amides Tetrazoles Thiohemiaminal derivatives 1,4-diazinane 1-hydroxy-2-unsubstituted benzenoid Alkylarylthioether Alpha peptide Alpha-amino acid amide Alpha-amino acid or derivatives Aromatic heteropolycyclic compound Aryl thioether Azacycle Azetidine Azole Benzenoid Beta-lactam Carbonic acid derivative Carbonyl group Carboxamide group Carboxylic acid Cephalosporin Cephem Dialkylthioether Dicarboximide Dioxopiperazine Hemithioaminal Heteroaromatic compound Hydrocarbon derivative Lactam Meta-thiazine Monocarboxylic acid or derivatives Monocyclic benzene moiety N-acyl urea N-acyl-alpha amino acid or derivatives N-alkylpiperazine N-carbamoyl-alpha-amino acid or derivatives N-substituted-alpha-amino acid Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Organosulfur compound Phenol Phenylacetamide Piperazine Piperazine-1-carboxamide Secondary carboxylic acid amide Sulfenyl compound Tertiary carboxylic acid amide Tetrazole Thioether Urea Ureide Aromatic heteropolycyclic compounds Detected and Not Quantified Cefoperazone Drug Metabolism Action Pathway SMP0143709 logp -0.9 logp -0.11 ALOGPS logs -3.35 ALOGPS solubility 2.86e-01 g/l ALOGPS logp -0.9 ChemAxon pka_strongest_acidic 3.38 ChemAxon pka_strongest_basic -1.7 ChemAxon iupac (6R,7R)-7-{2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetamido}-3-{[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid ChemAxon average_mass 645.667 ChemAxon mono_mass 645.142400265 ChemAxon smiles [H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)C(NC(=O)N1CCN(CC)C(=O)C1=O)C1=CC=C(O)C=C1)C(O)=O ChemAxon formula C25H27N9O8S2 ChemAxon inchi InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15?,16-,22-/m1/s1 ChemAxon inchikey GCFBRXLSHGKWDP-WTKTZPJXSA-N ChemAxon polar_surface_area 220.26 ChemAxon refractivity 169.06 ChemAxon polarizability 62.62 ChemAxon rotatable_bond_count 9 ChemAxon acceptor_count 11 ChemAxon donor_count 4 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f727873d5d8> DB01329 44187 BE0002393 BE0000488 BE0003579 BE0000588 BE0003685 BE0002063 BE0000744 BE0003686 BE0003687