1.0 2016-05-25 18:27:10 UTC 2026-08-18 11:54:56 UTC Mephentermine SmallMolecule Mephentermine is an organic compound with the chemical formula C11H17N and an average molecular weight of 163.26 g/mol. Mephentermine belongs to the phenethylamines, a subclass of benzene and substituted derivatives within the organic compounds. It is classified under the superclass of benzenoids. The compound is recorded as being found in or released from 13 different sources. These include household cleaning and consumer products, specifically tobacco smoke filters and non electric simulated smoking devices. It is also associated with electrical and electronic equipment, including electrodes, antennas, electric switches, electrically stimulated smoking devices, emergency protective devices, and five additional sources. Within healthcare, pharmaceuticals, and veterinary products, it is identified as a cardiac stimulant, excluding cardiac glycosides. Recorded routes of exposure for the substance include intravenous and intramuscular administration. Mephentermine interacts with 10 recorded protein targets. It acts as an agonist of the Alpha-1D adrenergic receptor (ADRA1D), as well as the Alpha-2A (ADRA2A), Alpha-2B (ADRA2B), and Alpha-2C (ADRA2C) adrenergic receptors, along with six other proteins. C11H17N 163.2594 163.136099549 methyl(2-methyl-1-phenylpropan-2-yl)amine mephentermine 100-92-5 CNC(C)(C)CC1=CC=CC=C1 InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3 RXQCGGRTAILOIN-UHFFFAOYSA-N Organic compounds Benzenoids Benzene and substituted derivatives Phenethylamines Amphetamines and derivatives Aralkylamines Dialkylamines Hydrocarbon derivatives Organopnictogen compounds Phenylpropanes Amine Amphetamine or derivatives Aralkylamine Aromatic homomonocyclic compound Hydrocarbon derivative Organic nitrogen compound Organonitrogen compound Organopnictogen compound Phenylpropane Secondary aliphatic amine Secondary amine Aromatic homomonocyclic compounds amphetamines Detected and Not Quantified Mephentermine Drug Metabolism Action Pathway SMP0143729 logp 2.52 logp 2.54 ALOGPS logs -2.55 ALOGPS solubility 4.57e-01 g/l ALOGPS logp 2.52 ChemAxon pka_strongest_basic 10.3 ChemAxon iupac methyl(2-methyl-1-phenylpropan-2-yl)amine ChemAxon average_mass 163.2594 ChemAxon mono_mass 163.136099549 ChemAxon smiles CNC(C)(C)CC1=CC=CC=C1 ChemAxon formula C11H17N ChemAxon inchi InChI=1S/C11H17N/c1-11(2,12-3)9-10-7-5-4-6-8-10/h4-8,12H,9H2,1-3H3 ChemAxon inchikey RXQCGGRTAILOIN-UHFFFAOYSA-N ChemAxon polar_surface_area 12.03 ChemAxon refractivity 53.12 ChemAxon polarizability 19.79 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 1 ChemAxon donor_count 1 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225b191a0> DB01365 3677 3549 BE0000289 BE0000572 BE0000342 BE0000715 BE0000501 BE0000575 BE0000694 BE0000172 BE0001012 BE0000756