1.0 2016-05-25 18:28:11 UTC 2026-08-17 23:40:18 UTC Tazobactam SmallMolecule Tazobactam is an organic compound with the formula C10H12N4O5S and an average molecular weight of 300.29 g/mol. Tazobactam belongs to the amino acids, peptides, and analogues, a subclass of carboxylic acids and derivatives within the organic compounds. The compound acts as an inhibitor for four recorded protein targets: Beta-lactamase TEM (bla), Beta-lactamase Ohio-1, Beta-lactamase SHV-1 (bla), and Beta-lactamase (blaZ). Exposure to Tazobactam can occur through oral, intravenous, parenteral, and inhalation routes. Tazobactam is found in or released from nine recorded sources. These include healthcare, pharmaceuticals, and veterinary products, specifically antibiotics and penicillins. It is also associated with food, food processing, and cookware, specifically the processing of meats, as well as drinking water and water supply. Additionally, the compound is found in household cleaning and consumer products, such as other smoking requisites and non-electric simulated smoking devices, and in electrical and electronic equipment, including video games, amplifiers, and television systems. 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, (2S,3S,5R)- C10H12N4O5S 300.291 300.052840204 (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4λ⁶-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid tazobactam 89786-04-9 [H][C@@]12CC(=O)N1[C@@H](C(O)=O)[C@](C)(CN1C=CN=N1)S2(=O)=O InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1 LPQZKKCYTLCDGQ-WEDXCCLWSA-N Organic compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Alpha amino acids and derivatives Azacyclic compounds Azetidines Carbonyl compounds Carboxylic acids Heteroaromatic compounds Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organonitrogen compounds Organopnictogen compounds Penams Sulfones Tertiary carboxylic acid amides Thiazolidines Triazoles 1,2,3-triazole Alpha-amino acid or derivatives Aromatic heteropolycyclic compound Azacycle Azetidine Azole Beta-lactam Carbonyl group Carboxamide group Carboxylic acid Heteroaromatic compound Hydrocarbon derivative Lactam Monocarboxylic acid or derivatives Organic nitrogen compound Organic oxide Organic oxygen compound Organoheterocyclic compound Organonitrogen compound Organooxygen compound Organopnictogen compound Penam Sulfone Tertiary carboxylic acid amide Thiazolidine Aromatic heteropolycyclic compounds penicillanic acids triazoles Detected and Not Quantified Tazobactam Drug Metabolism Action Pathway SMP0143805 logp -1.4 logp -1.80 ALOGPS logs -1.50 ALOGPS solubility 9.59e+00 g/l ALOGPS logp -1.4 ChemAxon pka_strongest_acidic 2.86 ChemAxon pka_strongest_basic 0.73 ChemAxon iupac (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4λ⁶-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ChemAxon average_mass 300.291 ChemAxon mono_mass 300.052840204 ChemAxon smiles [H][C@@]12CC(=O)N1[C@@H](C(O)=O)[C@](C)(CN1C=CN=N1)S2(=O)=O ChemAxon formula C10H12N4O5S ChemAxon inchi InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1 ChemAxon inchikey LPQZKKCYTLCDGQ-WEDXCCLWSA-N ChemAxon polar_surface_area 122.46 ChemAxon refractivity 74.82 ChemAxon polarizability 26.22 ChemAxon rotatable_bond_count 3 ChemAxon acceptor_count 7 ChemAxon donor_count 1 ChemAxon physiological_charge -1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225a2fb40> DB01606 123630 110216 BE0001568 BE0009681 BE0002015 BE0000302