1.0 2016-05-25 18:29:46 UTC 2026-05-14 18:22:59 UTC Desvenlafaxine SmallMolecule Desvenlafaxine is an organic compound with the formula C16H25NO2 and an average molecular weight of 263.38 g/mol. Desvenlafaxine belongs to the alcohols and polyols, a subclass of organooxygen compounds within the organic compounds. This compound is found in or released from healthcare, pharmaceuticals, and veterinary products, specifically as an antidepressant, and is administered via oral exposure. It acts on three recorded protein targets, serving as an inhibitor of the sodium-dependent serotonin transporter (SLC6A4), the sodium-dependent noradrenaline transporter (SLC6A2), and the sodium-dependent dopamine transporter (SLC6A3). 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol C16H25NO2 263.3752 263.188529049 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol desvenlafaxine 93413-62-8 CN(C)CC(C1=CC=C(O)C=C1)C1(O)CCCCC1 InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 KYYIDSXMWOZKMP-UHFFFAOYSA-N Organic compounds Organic oxygen compounds Organooxygen compounds Alcohols and polyols Cyclohexanols 1,3-aminoalcohols 1-hydroxy-2-unsubstituted benzenoids Aralkylamines Benzene and substituted derivatives Cyclic alcohols and derivatives Hydrocarbon derivatives Organopnictogen compounds Tertiary alcohols Trialkylamines 1,3-aminoalcohol 1-hydroxy-2-unsubstituted benzenoid Amine Aralkylamine Aromatic homomonocyclic compound Benzenoid Cyclic alcohol Cyclohexanol Hydrocarbon derivative Monocyclic benzene moiety Organic nitrogen compound Organonitrogen compound Organopnictogen compound Phenol Tertiary alcohol Tertiary aliphatic amine Tertiary amine Aromatic homomonocyclic compounds cyclohexanols phenols tertiary amino compound Detected and Not Quantified logp 2.29 logp 2.60 ALOGPS logs -2.27 ALOGPS solubility 1.40e+00 g/l ALOGPS logp 2.29 ChemAxon pka_strongest_acidic 10.11 ChemAxon pka_strongest_basic 8.87 ChemAxon iupac 4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol ChemAxon average_mass 263.3752 ChemAxon mono_mass 263.188529049 ChemAxon smiles CN(C)CC(C1=CC=C(O)C=C1)C1(O)CCCCC1 ChemAxon formula C16H25NO2 ChemAxon inchi InChI=1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3 ChemAxon inchikey KYYIDSXMWOZKMP-UHFFFAOYSA-N ChemAxon polar_surface_area 43.7 ChemAxon refractivity 78.54 ChemAxon polarizability 30.32 ChemAxon rotatable_bond_count 4 ChemAxon acceptor_count 3 ChemAxon donor_count 2 ChemAxon physiological_charge 1 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7225eab228> DB06700 12018336 BE0000749 BE0000486 BE0000647