1.0 2016-05-25 18:30:32 UTC 2026-08-22 05:25:31 UTC Tafluprost SmallMolecule Tafluprost is an organic compound with the formula C25H34F2O5 and an average molecular weight of 452.53 g/mol. Tafluprost belongs to the eicosanoids, a subclass of fatty acyls within the organic compounds. In an industrial capacity, the substance is used as a softener and conditioner. The compound is found in healthcare, pharmaceuticals, and veterinary products, specifically within miotics and antiglaucoma preparations, where the recorded exposure route is ophthalmic. Regarding its biological activity, tafluprost acts as an agonist of the prostaglandin F2-alpha receptor (PTGFR). C25H34F2O5 452.5313 452.237430608 propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoate tafluprost 209860-87-7 CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1 InChI=1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26,27)17-31-19-10-6-5-7-11-19/h3,5-8,10-11,14-15,18,20-23,28-29H,4,9,12-13,16-17H2,1-2H3/b8-3-,15-14+/t20-,21-,22+,23-/m1/s1 WSNODXPBBALQOF-VEJSHDCNSA-N Organic compounds Lipids and lipid-like molecules Fatty Acyls Eicosanoids Prostaglandins and related compounds Alkyl aryl ethers Alkyl fluorides Carbonyl compounds Carboxylic acid esters Cyclic alcohols and derivatives Cyclopentanols Fatty acid esters Hydrocarbon derivatives Monocarboxylic acids and derivatives Organic oxides Organofluorides Phenol ethers Phenoxy compounds Alcohol Alkyl aryl ether Alkyl fluoride Alkyl halide Aromatic homomonocyclic compound Benzenoid Carbonyl group Carboxylic acid derivative Carboxylic acid ester Cyclic alcohol Cyclopentanol Ether Fatty acid ester Hydrocarbon derivative Monocarboxylic acid or derivatives Monocyclic benzene moiety Organic oxide Organic oxygen compound Organofluoride Organohalogen compound Organooxygen compound Phenol ether Phenoxy compound Prostaglandin skeleton Secondary alcohol Aromatic homomonocyclic compounds carboxylic ester organofluorine compound prostaglandins Falpha Detected and Not Quantified Tafluprost Drug Metabolism Action Pathway SMP0144175 Tafluprost Action Pathway SMP0175201 logp 4.29 logp 4.46 ALOGPS logs -4.93 ALOGPS solubility 5.28e-03 g/l ALOGPS logp 4.29 ChemAxon pka_strongest_acidic 14.51 ChemAxon pka_strongest_basic -2.9 ChemAxon iupac propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl]hept-5-enoate ChemAxon average_mass 452.5313 ChemAxon mono_mass 452.237430608 ChemAxon smiles CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(F)(F)COC1=CC=CC=C1 ChemAxon formula C25H34F2O5 ChemAxon inchi InChI=1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26,27)17-31-19-10-6-5-7-11-19/h3,5-8,10-11,14-15,18,20-23,28-29H,4,9,12-13,16-17H2,1-2H3/b8-3-,15-14+/t20-,21-,22+,23-/m1/s1 ChemAxon inchikey WSNODXPBBALQOF-VEJSHDCNSA-N ChemAxon polar_surface_area 75.99 ChemAxon refractivity 120.59 ChemAxon polarizability 48.65 ChemAxon rotatable_bond_count 13 ChemAxon acceptor_count 4 ChemAxon donor_count 2 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7267446368> DB08819 6433101 4938289 BE0000610