1.0 2016-05-25 22:40:07 UTC 2026-08-19 08:47:12 UTC Isoflavones SmallMolecule Isoflavones belongs to the isoflav-2-enes, a subclass of isoflavonoids within the organic compounds. This compound has the formula C15H10O2 and an average molecular weight of 222.24 g/mol. Biologically, it serves as a nutrient (PMC4713194), an antioxidant (PMC13249380), and a protective agent (PMC11435217). It acts as an agonist for two protein targets: Peroxisome proliferator-activated receptor gamma (PPARG) and Peroxisome proliferator-activated receptor alpha (PPARA). Isoflavones are found in 17 recorded sources, including ceilings in building and construction; antennas, magnets, radio transmission systems, and thin magnetic films in electrical and electronic equipment; cigar cigarettes, tobacco product cases, pipe accessories, and other smoking requisites in household cleaning and consumer products; and food processing and cookware, specifically the preparation of malt, vinegar, wine or sparkling wine, molasses and its treatment, and fermentation processes for beer. Regarding health effects, isoflavones are associated with male infertility (PMC10390305), prostate cancer (PMC4153070), a decrease in cancer (PMC5666732), and a decrease in endometrial cancer (PMC11303474, PMC4801991). The compound is used as a treatment for diabetes mellitus (PMC10646315) and hypertension (PMC13462034). Furthermore, it has demonstrated therapeutic effects on blood pressure (PMC11605795), cancer (PMC4713194, PMC7126989), prostate cancer (PMC12858508), neurological dysfunction (PMC13249380), and breast cancer (PMC11605795, PMC11755457, PMC11857983). C15H10O2 222.243 222.068079562 3-phenyl-4H-chromen-4-one isoflavone 574-12-9 O=C1C(=COC2=CC=CC=C12)C1=CC=CC=C1 InChI=1S/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H GOMNOOKGLZYEJT-UHFFFAOYSA-N Organic compounds Phenylpropanoids and polyketides Isoflavonoids Isoflav-2-enes Isoflavones Benzene and substituted derivatives Chromones Heteroaromatic compounds Hydrocarbon derivatives Organic oxides Organooxygen compounds Oxacyclic compounds Pyranones and derivatives 1-benzopyran Aromatic heteropolycyclic compound Benzenoid Benzopyran Chromone Heteroaromatic compound Hydrocarbon derivative Isoflavone Monocyclic benzene moiety Organic oxide Organic oxygen compound Organoheterocyclic compound Organooxygen compound Oxacycle Pyran Pyranone Aromatic heteropolycyclic compounds Isoflavonoids a small molecule isoflavones Detected and Not Quantified logp 3.34 logp 3.51 ALOGPS logs -4.42 ALOGPS solubility 8.43e-03 g/l ALOGPS logp 3.34 ChemAxon pka_strongest_basic -5.3 ChemAxon iupac 3-phenyl-4H-chromen-4-one ChemAxon average_mass 222.243 ChemAxon mono_mass 222.068079562 ChemAxon smiles O=C1C(=COC2=CC=CC=C12)C1=CC=CC=C1 ChemAxon formula C15H10O2 ChemAxon inchi InChI=1S/C15H10O2/c16-15-12-8-4-5-9-14(12)17-10-13(15)11-6-2-1-3-7-11/h1-10H ChemAxon inchikey GOMNOOKGLZYEJT-UHFFFAOYSA-N ChemAxon polar_surface_area 26.3 ChemAxon refractivity 65.74 ChemAxon polarizability 23.64 ChemAxon rotatable_bond_count 1 ChemAxon acceptor_count 2 ChemAxon donor_count 0 ChemAxon physiological_charge 0 ChemAxon formal_charge 0 ChemAxon #<HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7224838b80> DB12007 72304 65255 BE0000071 BE0000215