<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <version>1.0</version>
  <creation_date>2016-05-26 00:43:09 UTC</creation_date>
  <update_date>2026-04-16 22:46:27 UTC</update_date>
  <accession/>
  <common_name>Ammonium hydroxide</common_name>
  <class>SmallMolecule</class>
  <description>Ammonium hydroxide (H5NO) is an inorganic compound with an average molecular weight of 35.05 g/mol. Ammonium hydroxide belongs to the non-metal hydroxides, a subclass of non-metal oxoanionic compounds within the inorganic compounds.

This substance is utilized in various industrial capacities, serving as a pH regulating agent, surfactant, diluent, binder, preservative, cleaning agent, stabilizing agent, adhesion/cohesion promoter, surface modifier, and leavening agent. Additionally, it is used as a buffer (PMC7918373) and a solvent (PMC8630709).

Ammonium hydroxide is found in or released from 43 recorded sources. Within electrical and electronic equipment, it is associated with amplifiers, antennas, coils, auxiliary devices, and adjustable resistors, among 20 others. In the category of food, food processing, and cookware, it is linked to the processing of meats and fermentation processes for beer, as well as the preparation of vinegar, malt, and wine or sparkling wine. It is also present in household cleaning and consumer products, including soap detergents, bleaching agents, cigar cigarettes, pipe accessories, and other smoking requisites. Further sources include household items such as coins, as well as building and construction materials including tents or canopies, ceilings, fencing, floors, and stairs and ramps.</description>
  <categories/>
  <types/>
  <synonyms/>
  <chemical_formula>H5NO</chemical_formula>
  <average_molecular_weight>35.0458</average_molecular_weight>
  <monisotopic_moleculate_weight>35.037113787</monisotopic_moleculate_weight>
  <iupac_name>ammonium hydroxide</iupac_name>
  <traditional_iupac>ammonium hydroxide</traditional_iupac>
  <cas_registry_number>1336-21-6</cas_registry_number>
  <smiles>[NH4+].[OH-]</smiles>
  <inchi>InChI=1S/H3N.H2O/h1H3;1H2</inchi>
  <inchikey>VHUUQVKOLVNVRT-UHFFFAOYSA-N</inchikey>
  <taxonomy>
    <kingdom>Inorganic compounds</kingdom>
    <super_class>Homogeneous non-metal compounds</super_class>
    <class>Non-metal oxoanionic compounds</class>
    <sub_class>Non-metal hydroxides</sub_class>
    <direct_parent>Non-metal hydroxides</direct_parent>
    <alternate_parents>
      <alternative_parent>Inorganic hydrides</alternative_parent>
      <alternative_parent>Inorganic oxides</alternative_parent>
      <alternative_parent>Inorganic salts</alternative_parent>
    </alternate_parents>
    <substituents>
      <substituent>Inorganic hydride</substituent>
      <substituent>Inorganic oxide</substituent>
      <substituent>Inorganic salt</substituent>
      <substituent>Non-metal hydroxide</substituent>
    </substituents>
    <molecular_framework/>
    <descriptors>
      <descriptor>inorganic hydroxy compound</descriptor>
    </descriptors>
  </taxonomy>
  <status>Detected and Not Quantified</status>
  <origin/>
  <cellular_locations/>
  <biofluid_locations/>
  <tissue_locations/>
  <pathways/>
  <state/>
  <appearance/>
  <experimental_properties/>
  <predicted_properties>
    <property>
      <kind>logp</kind>
      <value>-0.98</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>pka_strongest_basic</kind>
      <value>8.86</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>iupac</kind>
      <value>ammonium hydroxide</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>average_mass</kind>
      <value>35.0458</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>mono_mass</kind>
      <value>35.037113787</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>smiles</kind>
      <value>[NH4+].[OH-]</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formula</kind>
      <value>H5NO</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchi</kind>
      <value>InChI=1S/H3N.H2O/h1H3;1H2</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>inchikey</kind>
      <value>VHUUQVKOLVNVRT-UHFFFAOYSA-N</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polar_surface_area</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>refractivity</kind>
      <value>16.31</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>polarizability</kind>
      <value>2.38</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>rotatable_bond_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>acceptor_count</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>donor_count</kind>
      <value>1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>physiological_charge</kind>
      <value>1</value>
      <source>ChemAxon</source>
    </property>
    <property>
      <kind>formal_charge</kind>
      <value>0</value>
      <source>ChemAxon</source>
    </property>
  </predicted_properties>
  <route_of_exposure/>
  <mechanism_of_toxicity/>
  <metabolism/>
  <toxicity/>
  <lethaldose/>
  <carcinogenicity/>
  <use_source/>
  <min_risk_level/>
  <health_effects>#&lt;HealthEffect::ActiveRecord_Associations_CollectionProxy:0x00007f7283f1c960&gt;</health_effects>
  <symptoms/>
  <treatment/>
  <drugbank_id/>
  <hmdb_id/>
  <pubchem_compound_id>14923</pubchem_compound_id>
  <chembl_id/>
  <chemspider_id/>
  <kegg_id/>
  <uniprot_id/>
  <omim_id/>
  <chebi_id/>
  <biocyc_id/>
  <ctd_id/>
  <stitch_id/>
  <actor_id/>
  <pdb_id/>
  <wikipidia/>
  <general_references/>
  <targets/>
</compound>
